Sun Kangkang, Shan Hongbin, Neumann Helfried, Lu Guo-Ping, Beller Matthias
School of Chemistry and Chemical Engineering, Nanjing University of Science & Technology, Xiaolingwei 200, Nanjing, 210094, P. R. China.
Leibniz-Institute für Katalyse, Albert-Einstein-Str. 29a, 18059, Rostock, Germany.
Nat Commun. 2022 Apr 6;13(1):1848. doi: 10.1038/s41467-022-29074-1.
Zeolitic imidazolate frameworks derived Fe-N-C catalysts with isolated single iron atoms have been synthesized and applied for selective ammoxidation reactions. For the preparation of the different Fe-based materials, benzylamine as an additive proved to be essential to tune the morphology and size of ZIFs resulting in uniform and smaller particles, which allow stable atomically dispersed Fe-N active sites. The optimal catalyst Fe-N-C achieves an efficient synthesis of various aryl, heterocyclic, allylic, and aliphatic nitriles from alcohols in water under very mild conditions. With its chemoselectivity, recyclability, high efficiency under mild conditions this new system complements the toolbox of catalysts for nitrile synthesis, which are important intermediates with many applications in life sciences and industry.
已合成出具有孤立单铁原子的沸石咪唑酯骨架衍生的Fe-N-C催化剂，并将其应用于选择性氨氧化反应。在制备不同的铁基材料时，事实证明，作为添加剂的苄胺对于调节沸石咪唑酯骨架的形态和尺寸至关重要，从而可得到均匀且更小的颗粒，这些颗粒能够使铁氮活性位点稳定地原子分散。最优催化剂Fe-N-C能够在非常温和的条件下，于水中由醇高效合成各种芳基、杂环、烯丙基和脂肪族腈。凭借其化学选择性、可回收性以及在温和条件下的高效率，这个新体系为腈合成催化剂工具箱增添了新工具，腈是在生命科学和工业中有许多应用的重要中间体。
