Barrachina Borja, Lopez-Picado Amanda, Albinarrate Ania, Iriarte Ibai, Remón María, Basora Misericordia, Ferreira-Laso Lourdes, Blanco Del Val Beatriz, Andrés Judith, Paredes Sofia Paz, Pharm Raquel Cobos Campos
Associated Clinicians Research Group, Bioaraba Health Research Institute, Vitoria-Gasteiz, Spain.
Faculty of Health, International University of La Rioja, Logroño, Spain.
Ir J Med Sci. 2023 Feb;192(1):327-333. doi: 10.1007/s11845-022-02946-7. Epub 2022 Apr 7.
Among various methods for estimating blood loss, the gravimetric method is the most accurate; however, its use in routine practice is complicated. Although several equations have been proposed for this purpose, there is no consensus on the most suitable.
A cross-sectional study was conducted in seven secondary and tertiary hospitals between March and July 2018 including all patients undergoing total hip arthroplasty or hip prosthesis replacement under general or regional anaesthesia. We compared blood loss estimates obtained using the gravimetric method (weighing gauzes and pads and measuring volumes of blood collected by suction during surgery) and using three different equations, two of which considered intravenous fluids (CRYS 3.5 and 1.5) and a third which did not (the traditional equation). Additionally, intraclass correlation coefficients (ICCs) and Bland-Altman plots were used.
The mean blood loss estimated using the gravimetric method was 513.7 ± 421.7 mL, while estimates calculated using the CRYS 3.5, CRYS 1.5 and traditional equations were 737.2 ± 627.4, 420.8 ± 636.2 and 603.4 ± 386.3 mL, respectively. Comparing these results, we found low levels of agreement (based on ICCs), except when using the traditional equation (ICC: 0.517). The limits of agreement comparing external blood loss with the estimates from the equations ranged from - 1655.6 to 1459.2 in the case of the CRYS 1.5 equation to - 839.6 to 1008.4 in the case of the traditional equation.
For use in clinical practice, haematological index-based equations, regardless of whether they consider fluids administered, do not show sufficiently strong correlations with gravimetric estimates of intraoperative blood loss.
在各种估计失血量的方法中,重量法最为准确;然而,其在常规实践中的应用较为复杂。尽管为此提出了几个公式,但对于最合适的公式尚无共识。
2018年3月至7月在7家二级和三级医院进行了一项横断面研究,纳入所有在全身或区域麻醉下接受全髋关节置换术或髋关节假体置换术的患者。我们比较了使用重量法(称量纱布和垫子并测量手术期间通过吸引收集的血液量)和使用三个不同公式所获得的失血量估计值,其中两个公式考虑了静脉输液(CRYS 3.5和1.5),第三个公式未考虑(传统公式)。此外,还使用了组内相关系数(ICC)和Bland-Altman图。
使用重量法估计的平均失血量为513.7±421.7毫升,而使用CRYS 3.5、CRYS 1.5和传统公式计算的估计值分别为737.2±627.4、420.8±636.2和603.4±386.3毫升。比较这些结果,我们发现一致性水平较低(基于ICC),使用传统公式时除外(ICC:0.517)。将外部失血量与公式估计值进行比较时,一致性界限在CRYS 1.5公式的情况下为-1655.6至1459.2,在传统公式的情况下为-839.6至1008.4。
在临床实践中,基于血液学指标的公式,无论是否考虑所输注的液体,与术中失血量的重量法估计值均未显示出足够强的相关性。