Divya Midha, Narkeesh Arumugam
Department of Physiotherapy, Punjabi University, Patiala, Punjab, India.
Neurosci Insights. 2022 Mar 30;17:26331055221087741. doi: 10.1177/26331055221087741. eCollection 2022.
There has been rapid drift of rehabilitation professionals toward the clinical use of technology aided electrical interventions. Brain is a cortical hub of functionally related neural connections. Motor learning entails strong interaction with the cognitive domains. So better outcomes may be expected by optimally targeting functionally correlated areas simultaneously through tDCS.
To determine the therapeutic effect of Multi Channel tDCS in combination with Functional electrical stimulation, SaeboFlex and conventional rehabilitation on recovery of Cognitive Domains, Motor Functions of Paretic Hand, and Gait in individuals with subacute Stroke.
This is prospective, randomized, double blind controlled clinical trial. Subacute Stroke Survivors with the age Group (40-75 years) will constitute the Population of the study. Participants will be randomly allocated to experimental or control group. Participants of Experimental group will receive Multi channel tDCS, Functional electrical stimulation, Saebo Flex Training and conventional rehabilitation. Participants of the group B will receive FES, training with SaeboFlex, conventional physiotherapy intervention similar to as given to the participants of group A and sham multi channel tDCS.
The primary outcome measures of the study will be Fugl Meyer assessment, Electroencephalogram and secondary outcome measures of the study will be Grip strength, Pinch strength, Nine hole peg test( NHPT), Wisconsin gait scale, Montreal cognitive assessment, Electroencephaloraphy to observe the cortical changes and tDCS adverse effect questionnaire and stroke specific quality of Life scale.
The primary analysis of the study will be done at the end of 4 weeks. Statistical analysis of data will be done using SPSS Version 22 with the help of a statistician.
An insight into the therapeutic interventions augmenting, cognitive and motor domains simultaneously may yield better outcomes in the field of stroke rehabilitation thereby improving quality of life of stroke survivors.
康复专业人员迅速倾向于在临床中使用技术辅助的电干预。大脑是功能相关神经连接的皮质枢纽。运动学习需要与认知领域进行强烈互动。因此，通过经颅直流电刺激（tDCS）同时最佳地靶向功能相关区域，可能会获得更好的结果。
确定多通道tDCS联合功能性电刺激、SaeboFlex和传统康复对亚急性脑卒中患者认知领域恢复、患侧手运动功能和步态的治疗效果。
这是一项前瞻性、随机、双盲对照临床试验。年龄在40 - 75岁的亚急性脑卒中幸存者将构成研究人群。参与者将被随机分配到实验组或对照组。实验组参与者将接受多通道tDCS、功能性电刺激、Saebo Flex训练和传统康复。B组参与者将接受功能性电刺激、SaeboFlex训练、与A组参与者相同的传统物理治疗干预以及假多通道tDCS。
该研究的主要结果指标将是Fugl Meyer评估、脑电图，次要结果指标将是握力、捏力、九孔插板试验（NHPT）、威斯康星步态量表、蒙特利尔认知评估、脑电图以观察皮质变化以及tDCS不良反应问卷和脑卒中特定生活质量量表。
该研究的主要分析将在4周结束时进行。数据的统计分析将在统计学家的帮助下使用SPSS 22版完成。
深入了解同时增强认知和运动领域的治疗干预措施，可能会在脑卒中康复领域产生更好的效果，从而改善脑卒中幸存者的生活质量。
