Delépine G, Delépine N
Biomed Pharmacother. 1986;40(5):169-72.
The authors summarize the literature on the local treatment of Ewing's sarcoma. They remind us that including surgery in local treatment increases disease free survival rate by 20-25% while it reduces functional sequelae and radioinduced sarcoma risk. They underline the major interest of histologic examination of in bloc resected tumor to guide postoperative chemotherapy. They advocate that local treatment of Ewing's sarcoma should always be surgical and conservative with the help when necessary of massive homograft and lengthening prosthesis.
作者总结了尤因肉瘤局部治疗的相关文献。他们提醒我们，在局部治疗中加入手术可使无病生存率提高20%-25%，同时降低功能后遗症和放射性肉瘤的风险。他们强调整块切除肿瘤的组织学检查对指导术后化疗的重要意义。他们主张尤因肉瘤的局部治疗应始终采用手术方式且较为保守，必要时可借助大块同种异体移植和延长假体。
