Schwenk H U, Hanssler L, Pesch H J
Med Klin. 1975 Dec 19;70(51-52):2069-74.
With eleven patients, for whom in the period 1967-74 a diagnosis of Ewing's sarcoma was confirmed, it was shown how by intensifying the chemo- and radiotherapy the survival time of some patients could be prolonged. At the same time surgical therapy has become less important. The diagnostical difficulties of the histomorphological differentiation of Ewing's sarcoma from lymphosarcoma are detailed on the example of another patient. A further general intensification of the chemo- and radiotherapy is not possible as the organism's limit of acute tolerance is already reached. Any future improvement on the results of treatment seems therefore only possible if combination therapy is modified to correspond to the particular needs of the individual patient.
1967年至1974年期间，有11例患者被确诊为尤因肉瘤，研究表明，通过强化化疗和放疗，部分患者的生存时间得以延长。与此同时，手术治疗的重要性有所降低。以另一例患者为例，详细阐述了尤因肉瘤与淋巴肉瘤在组织形态学鉴别诊断上的困难。由于已经达到机体急性耐受极限，进一步强化化疗和放疗已不可行。因此，只有根据个体患者的特殊需求调整联合治疗方案，未来治疗效果才有可能得到改善。
