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研究中重复经颅磁刺激(rPMS)方法质量清单:一项国际德尔菲研究。

Checklist on the Quality of the Repetitive Peripheral Magnetic Stimulation (rPMS) Methods in Research: An International Delphi Study.

作者信息

Schneider Cyril, Zangrandi Andrea, Sollmann Nico, Bonfert Michaela Veronika, Beaulieu Louis-David

机构信息

Noninvasive Stimulation Laboratory (NovaStim), Neuroscience Division, Research Center of CHU de Québec-Université Laval, Quebec City, QC, Canada.

Department of Rehabilitation, Faculty of Medicine, Université Laval, Quebec City, QC, Canada.

出版信息

Front Neurol. 2022 Mar 22;13:852848. doi: 10.3389/fneur.2022.852848. eCollection 2022.

Abstract

An increasing number of clinical research studies have used repetitive peripheral magnetic stimulation (rPMS) in recent years to alleviate pain or improve motor function. rPMS is non-invasive, painless, and administrated over peripheral nerve, spinal cord roots, or a muscle using a coil affixed to the skin and connected to a rapid-rate magnetic stimulator. Despite the clinical impact and scientific interest, the methodological inconsistencies or incomplete details and findings between studies could make the rPMS demonstration difficult to replicate. Given the lack of guidelines in rPMS literature, the present study aimed at developing a checklist to improve the quality of rPMS methods in research. An international panel of experts identified among those who had previously published on the topic were enrolled in a two-round web-based Delphi study with the aim of reaching a consensus on the items that should be reported or controlled in any rPMS study. The consensual rPMS checklist obtained comprises 8 subject-related items (e.g., age, sex), 16 methodological items (e.g., coil type, pulse duration), and 11 stimulation protocol items (e.g., paradigm of stimulation, number of pulses). This checklist will contribute to new interventional or exploratory rPMS research to guide researchers or clinicians on the methods to use to test and publish rPMS after-effects. Overall, the checklist will guide the peer-review process on the quality of rPMS methods reported in a publication. Given the dynamic nature of a consensus between international experts, it is expected that future research will affine the checklist.

摘要

近年来,越来越多的临床研究使用重复经颅磁刺激(rPMS)来缓解疼痛或改善运动功能。rPMS是非侵入性的、无痛的,通过固定在皮肤上并连接到快速磁刺激器的线圈对周围神经、脊髓神经根或肌肉进行刺激。尽管rPMS在临床方面具有影响力且引发了科学兴趣,但研究之间方法上的不一致或细节及结果不完整,可能导致rPMS的论证难以重复。鉴于rPMS文献中缺乏相关指南,本研究旨在制定一份清单,以提高rPMS研究方法的质量。一个由先前在该主题上发表过文章的专家组成的国际小组参与了两轮基于网络的德尔菲研究,目的是就任何rPMS研究中应报告或控制的项目达成共识。最终获得的共识性rPMS清单包括8个与受试者相关的项目(如年龄、性别)、16个方法学项目(如线圈类型、脉冲持续时间)和11个刺激方案项目(如刺激模式、脉冲数量)。这份清单将有助于新的rPMS干预性或探索性研究,指导研究人员或临床医生采用何种方法来测试和发表rPMS的后续效应。总体而言,该清单将指导对出版物中报告的rPMS方法质量的同行评审过程。鉴于国际专家之间共识的动态性质,预计未来的研究将完善这份清单。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fa8/8981720/9f314284688a/fneur-13-852848-g0001.jpg

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