超声引导经口和经皮核心针活检在口腔肿块患者中的疗效和安全性比较研究。
Comparative study on efficacy and safety of ultrasound guided transoral and transcutaneous core needle biopsy in patients with oral masses.
机构信息
Department of Ultrasound Medical Center, Sichuan Cancer Hospital Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610041, China.
出版信息
BMC Med Imaging. 2022 Apr 7;22(1):65. doi: 10.1186/s12880-022-00784-8.
BACKGROUND
Ultrasound (US) guided transoral biopsy is a novel and safe procedure for obtaining tissue in patients with oral masses. However, this procedure is less commonly used in comparison to US guided transcutaneous biopsy. The aim of this study is to compare the efficacy and safety of US-guided transoral and transcutaneous core needle biopsy (CNB) in patients with oral masses.
METHODS
From November 2019 to March 2021, consecutive patients with oral masses were randomly assigned to undergo US-guided transoral CNB (transoral group) and US-guided transcutaneous CNB from a submental approach (transcutaneous group). During the operation, procedure time, intra‑operative blood loss volume, diagnostic performance, rate of complications and pain level were recorded and compared.
RESULTS
There were 112 patients (62 in the transoral group and 50 in the transcutaneous group) evaluated in this study. The postprocedural complication rate of the transcutaneous group was significantly higher than the transoral group (24% vs. 0%, P = 0.000). There was no significant difference in accuracy (95.2% vs. 88%, P = 0.30), biopsy time (76 ± 12 s vs. 80 ± 13 s, p = 0.09), blood losses (2.6 ± 0.5 mL vs. 2.7 ± 0.4 mL, p = 0.17) and visual analogue score (p = 0.327 and p = 0.444 before and after the sampling procedure) between the two groups.
CONCLUSION
US-guided transoral CNB results in high rates of technical success and lower rates of postprocedural complications.
背景
超声（US）引导经口活检是一种获取口腔肿块患者组织的新型安全方法。然而，与 US 引导经皮活检相比，该方法的应用较少。本研究旨在比较 US 引导经口和经皮核心针活检（CNB）在口腔肿块患者中的疗效和安全性。
方法
从 2019 年 11 月至 2021 年 3 月，连续的口腔肿块患者被随机分配接受 US 引导经口 CNB（经口组）和颏下途径 US 引导经皮 CNB（经皮组）。在手术过程中，记录并比较手术时间、术中失血量、诊断性能、并发症发生率和疼痛程度。
结果
本研究共评估了 112 例患者（经口组 62 例，经皮组 50 例）。经皮组的术后并发症发生率明显高于经口组（24%比 0%，P=0.000）。准确性（95.2%比 88%，P=0.30）、活检时间（76±12 s 比 80±13 s，p=0.09）、出血量（2.6±0.5 mL 比 2.7±0.4 mL，p=0.17）和视觉模拟评分（采样前后 p=0.327 和 p=0.444）在两组间无显著差异。
结论
US 引导经口 CNB 技术成功率高，术后并发症发生率低。
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