Liu Zhuan, Lin Yixuan, Wu Jiani, Chen Diqun, Wu Xiaoyan, Lan Ying, Chen Zhihui
The Department of Endemic Diseases, Fujian Center for Disease Control and Prevention Fujian, No. 386 Chong'an Road, Fuzhou, 350012, Fujian, People's Republic of China.
The Department of Disease Control and Prevention, The First Hospital of Quanzhou Affiliated to Fujian Medical University, No.248-252, Dongjie Road, Quanzhou, 362000, Fujian, People's Republic of China.
Nutr Metab (Lond). 2022 Apr 7;19(1):27. doi: 10.1186/s12986-022-00656-6.
Urinary iodine concentration (UIC) is routinely used to evaluate the population iodine status while the uniform method for the individual level assessment is uncertain.
To explore the 24-h urinary iodine excretion (UIE) in five different periods of the day and the corresponding prediction equations respect by the use of creatinine-corrected UIC.
We collected 24-h, spot and fasting urine in five periods of the day to estimate 24-h UIE by the six different prediction equations. We compared the estimated creatinine-corrected UIC to the collected 24-h UIE and identified the most suitable equations in each period of the day.
Among the six different prediction equations, the equation of Kawasaki T was the best to estimate the 24-h UIE by fasting urine among Chinese adults. Among the five periods of time, the equation of Knudsen N was the best to estimate the 24-h UIE in the non-morning period.
Urinary iodine status at the individual level could be estimated by different creatinine-based equations at different periods of the day.
尿碘浓度（UIC）常用于评估人群碘营养状况，但个体水平评估的统一方法尚不确定。
通过使用肌酐校正的UIC，探索一天中五个不同时间段的24小时尿碘排泄量（UIE）及其相应的预测方程。
我们在一天中的五个时间段收集了24小时、即时和空腹尿液，通过六个不同的预测方程来估算24小时UIE。我们将估算的肌酐校正UIC与收集的24小时UIE进行比较，并确定一天中每个时间段最合适的方程。
在六个不同的预测方程中，川崎T方程是估算中国成年人空腹尿24小时UIE的最佳方程。在五个时间段中，克努森N方程是估算非早晨时间段24小时UIE的最佳方程。
一天中不同时间段可通过不同的基于肌酐的方程来估算个体水平的尿碘状况。
