Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Sweden.
Department of Medicine Solna, Clinical Epidemiology Unit, Karolinska Institutet, Karolinska University Hospital, Sweden.
Vaccine. 2022 May 3;40(20):2823-2827. doi: 10.1016/j.vaccine.2022.03.061. Epub 2022 Mar 29.
Vaccination against SARS-CoV-2 started in Region Stockholm, Sweden in December 2020 with those in long-term care facilities or receiving home care vaccinated first followed by those aged over 80 years. In this population-based, retrospective cohort study, we performed a Poisson regression to model the expected incidence of infections and deaths which we compared to the observed incidence and compared this to an unvaccinated control group of those aged 18-79 years. The aim of this study was to measure the early impact of the vaccination programme in Region Stockholm. Infections and deaths reduced substantially amongst the first two groups targeted for SARS-CoV-2 vaccination with an estimated total 3112 infections prevented, and 854 deaths prevented in these two groups from 4 weeks after the introduction of vaccination through to 2nd May 2021.
2020 年 12 月，瑞典斯德哥尔摩地区开始接种 SARS-CoV-2 疫苗，首先为长期护理机构或接受家庭护理的人群接种疫苗，然后为 80 岁以上人群接种疫苗。在这项基于人群的回顾性队列研究中，我们进行了泊松回归分析，以模拟感染和死亡的预期发生率，并将其与未接种疫苗的 18-79 岁年龄组对照组进行比较。本研究的目的是衡量斯德哥尔摩地区疫苗接种计划的早期影响。在针对 SARS-CoV-2 疫苗接种的前两组目标人群中，感染和死亡人数大幅减少，估计从接种疫苗开始的 4 周后至 2021 年 5 月 2 日，这两组人群共预防了 3112 例感染，预防了 854 例死亡。
