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诊断后 12 个月时 1 型糖尿病患儿和青少年血糖控制的预测因素。

Predictors of glycemic control in children and adolescents with type 1 diabetes at 12 months after diagnosis.

机构信息

Department of Pediatrics, University of Jordan, Amman, Jordan.

Pharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.

出版信息

Pediatr Diabetes. 2022 Sep;23(6):729-735. doi: 10.1111/pedi.13342. Epub 2022 Apr 20.


DOI:10.1111/pedi.13342
PMID:35393709
Abstract

Identifying risk factors for suboptimal glycemic control during the first year after diagnosis with type 1 diabetes (T1D) may provide early appropriate and individualized management. Our aim was to study possible predictors of early glycemic control during the first year after diagnosis with T1D in children and adolescents in Jordan. This is a retrospective study conducted through a review of medical records at Jordan University Hospital and the National Centre for Diabetes, Endocrinology and Genetics. Children and adolescents diagnosed with T1D at age younger than 16 years and with diabetes duration of at least 2 years were included. Demographic, clinical and socioeconomic factors were collected, in addition to glycosylated hemoglobin (HbA1c) values during the first year after diagnosis. Average age at diagnosis of the 337 patients who were enrolled in the study was 7.7 ± 3.8 years. HbA1c at diagnosis was 10.9 ± 1.9% (95.64 ± 20.76 mmol/mol). Factors such as the involvement of children's mothers in deciding insulin doses, higher mother's educational level and higher family monthly income were associated with better early glycemic control. HbA1c at 6 months after diagnosis, parental marital status and compliance to counting carbohydrates were significant predictors of glycemic control at 12 months after diagnosis. Many clinical and socioeconomic factors were associated with early glycemic control at 12 months after diagnosis. Modifiable risk factors must be addressed as early as possible to decrease future complications. Children with nonmodifiable risk factors should be identified early for closer observation and providing individualized diabetes care plan.

摘要

确定 1 型糖尿病(T1D)诊断后第一年血糖控制不佳的风险因素,可能有助于进行早期适当的个体化管理。我们的目的是研究约旦儿童和青少年 T1D 诊断后第一年早期血糖控制的可能预测因素。这是一项回顾性研究,通过审查约旦大学医院和国家糖尿病、内分泌学和遗传学中心的病历进行。纳入年龄小于 16 岁且糖尿病病程至少 2 年的 T1D 患儿。收集了人口统计学、临床和社会经济因素,以及诊断后第一年的糖化血红蛋白(HbA1c)值。纳入研究的 337 名患者的平均诊断年龄为 7.7±3.8 岁。诊断时的 HbA1c 为 10.9±1.9%(95.64±20.76mmol/mol)。患儿母亲参与决定胰岛素剂量、母亲受教育程度较高和家庭月收入较高等因素与早期血糖控制较好相关。诊断后 6 个月的 HbA1c、父母婚姻状况和碳水化合物计数依从性是诊断后 12 个月血糖控制的显著预测因素。许多临床和社会经济因素与诊断后 12 个月的早期血糖控制相关。必须尽早解决可改变的危险因素,以减少未来的并发症。对于不可改变的危险因素的患儿,应尽早识别,以便进行更密切的观察和提供个体化的糖尿病护理计划。

相似文献

[1]
Predictors of glycemic control in children and adolescents with type 1 diabetes at 12 months after diagnosis.

Pediatr Diabetes. 2022-9

[2]
Impact of Socioeconomic Characteristics on Metabolic Control in Children with Type 1 Diabetes in a Developing Country.

J Clin Res Pediatr Endocrinol. 2019-11-22

[3]
Factors predicting poor glycemic control in the first two years of childhood onset type 1 diabetes in a cohort from East London, UK: Analyses using mixed effects fractional polynomial models.

Pediatr Diabetes. 2020-3

[4]
Predictors of glycemic control in the first year of diagnosis of childhood onset type 1 diabetes: A systematic review of quantitative evidence.

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[5]
Predictors of Glycemic Control in Adolescents of Various Age Groups With Type 1 Diabetes.

J Nurs Res. 2015-12

[6]
Children's glycemic control: mother's knowledge and socioeconomic status.

Glob J Health Sci. 2013-10-29

[7]
The remission phase in adolescents and young adults with newly diagnosed type 1 diabetes mellitus: prevalence, predicting factors and glycemic control during follow-up.

Arch Endocrinol Metab. 2022-4-28

[8]
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J Pediatr Endocrinol Metab. 2022-6-27

[9]
Clinical outcomes in youth beyond the first year of type 1 diabetes: Results of the Pediatric Diabetes Consortium (PDC) type 1 diabetes new onset (NeOn) study.

Pediatr Diabetes. 2016-10-19

[10]
Above 40% of Polish children and young adults with type 1 diabetes achieve international HbA1c target - results of a nationwide cross-sectional evaluation of glycemic control: The PolPeDiab HbA1c study.

Pediatr Diabetes. 2021-11

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[1]
Parental Low Level of Education and Single-Parent Families as Predictors of Poor Control of Type 1 Diabetes in Children Followed in French Guiana.

Int J Environ Res Public Health. 2025-6-30

[2]
The pathophysiological link between type 1 diabetes and MASLD: insights into insulin resistance and liver dysfunction.

J Endocrinol Invest. 2025-6-27

[3]
Type 1 diabetes mellitus in children: Patient reported outcomes.

PLoS One. 2025-5-5

[4]
Effect on Glycemic Control of an Early Intensive Dietary Structured Education Program for Newly Diagnosed Children with Type 1 Diabetes in Jordan.

Pediatr Diabetes. 2023-4-28

[5]
Impact of COVID-19 lockdown on blood glucose levels in pediatric patients with type 1 diabetes mellitus.

Ann Pediatr Endocrinol Metab. 2025-2

[6]
Association of quality of life with medication adherence and glycemic control in patients with type 1 diabetes.

J Diabetes Metab Disord. 2023-11-27

[7]
Sociodemographic factors affecting glycaemic control in Finnish paediatric patients with type 1 diabetes.

Endocrinol Diabetes Metab. 2023-11

[8]
Narrowing the Divide: The Role of Telehealth in Type 1 Diabetes Care for Marginalized Communities.

J Diabetes Sci Technol. 2023-7

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