Department of Surgery, Päijät-Häme Central Hospital, Tampere University, Lahti, Finland.
Finnish Cardiovascular Research Center - Tampere, Tampere University, Arvo Ylpön Katu 34 (33520 Tampere), P.O. Box 100, FI-33014, Tampere, Finland.
J Clin Monit Comput. 2023 Feb;37(1):45-53. doi: 10.1007/s10877-022-00854-w. Epub 2022 Apr 8.
To evaluate the accuracy of heart rate variability (HRV) parameters obtained with a wrist-worn photoplethysmography (PPG) monitor in patients recovering from minimally invasive colon resection to investigate whether PPG has potential in postoperative patient monitoring. 31 patients were monitored for three days or until discharge or reoperation using a wrist-worn PPG monitor (PulseOn, Finland) with a Holter monitor (Faros 360, Bittium Biosignals, Finland) as a reference measurement device. Beat-to-beat intervals (BBI) and HRV information collected by PPG were compared with RR intervals (RRI) and HRV obtained from the ECG reference after removing artefacts and ectopic beats. The beat-to-beat mean error (ME) and mean absolute error (MAE) of good quality heartbeat intervals obtained by wrist PPG were estimated as - 1.34 ms and 10.4 ms respectively. A significant variation in the accuracy of the HRV parameters was found. In the time domain, SDNN (9.11%), TRI (11.4%) and TINN (11.1%) were estimated with low relative MAE, while RMSSD (34.3%), pNN50 (139%) and NN50 (188%) had higher errors. The logarithmic parameters in the frequency domain (VLF Log, LF Log and HF Log) exhibited the lowest relative error, and for non-linear parameters, SD2 (7.5%), DFA α1 (8.25%) and DFA α2 (4.71%) were calculated much more accurately than SD1 (34.3%). The wrist PPG shows some potential for use in a clinical setting. The accuracy of several HRV parameters analyzed post hoc was found sufficient to be used in further studies concerning postoperative recovery of patients undergoing laparoscopic colon resection, although there were large errors in many common HRV parameters such as RMSSD, pNN50 and NN50, rendering them unusable.ClinicalTrials.gov Identifier: NCT04996511, August 9, 2021, retrospectively registered.
评估腕戴光体积描记（PPG）监测仪在微创结肠切除术后恢复患者的心率变异性（HRV）参数的准确性，以探讨 PPG 是否具有术后患者监测的潜力。31 例患者使用腕戴 PPG 监测仪（PulseOn，芬兰）和 Holter 监测仪（Faros 360，Bittium Biosignals，芬兰）作为参考测量设备进行了三天或直至出院或再次手术的监测。PPG 采集的逐拍间期（BBI）和 HRV 信息与去除伪迹和异位搏动后从 ECG 参考获得的 RR 间期（RRI）和 HRV 进行了比较。腕戴 PPG 获得的高质量心跳间隔的逐拍平均误差（ME）和平均绝对误差（MAE）分别估计为-1.34ms 和 10.4ms。发现 HRV 参数的准确性存在显著差异。在时域中，SDNN（9.11%）、TRI（11.4%）和 TINN（11.1%）的相对 MAE 估计值较低，而 RMSSD（34.3%）、pNN50（139%）和 NN50（188%）的误差较高。频域中的对数参数（VLF Log、LF Log 和 HF Log）表现出最低的相对误差，对于非线性参数，SD2（7.5%）、DFAα1（8.25%）和 DFAα2（4.71%）的计算精度远高于 SD1（34.3%）。腕戴 PPG 在临床环境中具有一定的应用潜力。尽管 RMSSD、pNN50 和 NN50 等许多常见 HRV 参数存在较大误差，导致其无法使用，但事后分析发现，所分析的几个 HRV 参数的准确性足以用于进一步研究腹腔镜结肠切除术后患者的术后恢复。ClinicalTrials.gov 标识符：NCT04996511，2021 年 8 月 9 日，回顾性注册。
