巴西经典猪瘟病毒的系统发生学。
Phylodynamics of classical swine fever virus in Brazil.
机构信息
Laboratório Federal de Defesa Agropecuária de Minas Gerais, Pedro Leopoldo, Brazil.
Centro Universitário de Sete Lagoas, UNIFEMM, Sete Legoas, Minas Gerais, Brazil.
出版信息
Braz J Microbiol. 2022 Jun;53(2):1065-1075. doi: 10.1007/s42770-022-00724-2. Epub 2022 Apr 8.
The classical swine fever virus is the etiologic agent of one of the diseases with the greatest impact on swine farming worldwide. An extensive area of Brazil is considered free of the disease, but some states in Northeast Brazil have registered outbreaks since 2001. The objective of this study was to analyze the genetic variations of the virus and its spread over time and space. Partial sequences of the viral E2 protein obtained from samples collected during the Brazilian outbreaks were compared with sequences from the GenBank database (NCBI). The results demonstrated the continuous presence of the virus in the state of Ceará, with diffusion to at least two other states. The Brazilian Northeast virus presents specific polymorphisms that separate it from viruses isolated in other countries.
经典猪瘟病毒是对全球养猪业影响最大的疾病之一的病原体。巴西的大片地区被认为没有这种疾病，但自 2001 年以来，巴西东北部的一些州已经出现了疫情。本研究的目的是分析病毒的遗传变异及其随时间和空间的传播。从巴西疫情期间采集的样本中获得的病毒 E2 蛋白的部分序列与 GenBank 数据库（NCBI）中的序列进行了比较。结果表明，该病毒在塞阿拉州持续存在，并至少扩散到另外两个州。巴西东北部的病毒存在特定的多态性，使其与其他国家分离的病毒区分开来。
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