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严重急性呼吸综合征冠状病毒 2 相关出血性脑炎,类似疱疹脑炎。

SARS-CoV-2-associated haemorrhagic encephalitis mimicking Herpes encephalitis.

机构信息

Department of Neurology, BLK Super Speciality Hospital, New Delhi, Jaipur, Rajasthan, India.

出版信息

J Neurovirol. 2022 Apr;28(2):322-325. doi: 10.1007/s13365-021-01045-0. Epub 2022 Apr 8.

Abstract

Although acute encephalopathy is quite commonly seen in patients of SARS-CoV-2 infection, encephalitis characterised by brain inflammation is relatively rare. Encephalitis caused by Herpes simplex type 1 is the most common cause of identified sporadic encephalitis, and early diagnosis and prompt treatment can prevent the devastating outcome. In this brief communication, we report a case of SARS-CoV-2 associated haemorrhagic encephalitis mimicking herpes encephalitis. In today's pandemic era, it is especially important to distinguish herpes encephalitis from SARS-CoV-2-associated encephalitis as treatment and prognosis of both the conditions differ greatly. This case highlights the importance of suspecting SARS-CoV-2 infection in a patient presenting with clinical symptoms and brain imaging suggestive of Herpes encephalitis.

摘要

虽然急性脑病在 SARS-CoV-2 感染患者中很常见,但以脑炎症为特征的脑炎相对较少。单纯疱疹病毒 1 型引起的脑炎是已确定的散发性脑炎的最常见原因,早期诊断和及时治疗可以预防灾难性后果。在本简要报告中,我们报告了一例 SARS-CoV-2 相关出血性脑炎,其表现类似于疱疹性脑炎。在当前的大流行时代,区分疱疹性脑炎和 SARS-CoV-2 相关脑炎尤为重要,因为这两种疾病的治疗和预后有很大的不同。本病例强调了在出现临床症状和脑影像学提示疱疹性脑炎的患者中怀疑 SARS-CoV-2 感染的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f7b/8992395/adb939ca1992/13365_2021_1045_Fig1_HTML.jpg

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