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单胎妊娠中紧急宫颈环扎术采用两针与一针预防早产的比较。

Comparison of two stitches versus one stitch for emergency cervical cerclage to prevent preterm birth in singleton pregnancies.

作者信息

Xu Zhi-Min, Zhang Jun, Hong Xiao-Lan, Liu Jing, Yang Zhen-Zhen, Pan Mian

机构信息

Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.

出版信息

Int J Gynaecol Obstet. 2023 Jan;160(1):98-105. doi: 10.1002/ijgo.14213. Epub 2022 Apr 21.

Abstract

OBJECTIVE

To compare the efficacy of two stitches versus one stitch in women with emergency cervical cerclage.

METHODS

A retrospective case-control study of 26 women with singleton pregnancies who underwent emergency cervical cerclage before 26 weeks. A comparison was made between patients with two stitches versus one stitch at the time of cervical cerclage placement. The primary outcome was gestational age (GA) at delivery and preterm birth (PTB) before 37, 34, 32, 28, and 24 weeks.

RESULTS

Average GA at delivery in the two-stitches group was significantly greater than in the one-stitch group (32.71 ± 5.54 weeks vs 27.99 ± 4.70 weeks, P = 0.028). There were significant decreases in the incidence of spontaneous PTB at <34 weeks and less than 32 weeks in the two-stitches group (P = 0.034; P = 0.013, respectively). The neonatal intensive care unit (NICU) admissions rate and length of stay in the NICU in the two-stitches group were significantly reduced (P = 0.035 and P = 0.018, respectively). However, there was no significant difference in neonatal mortality between the two groups.

CONCLUSION

Compared with emergency cervical cerclage placement with one stitch, the procedure with two stitches can prolong the pregnancy and improve the neonatal prognosis more effectively.

摘要

目的

比较在进行紧急宫颈环扎术的女性中使用两针与一针的疗效。

方法

对26例单胎妊娠且在26周前接受紧急宫颈环扎术的女性进行回顾性病例对照研究。比较宫颈环扎术时采用两针与一针的患者。主要结局指标为分娩时的孕周(GA)以及37、34、32、28和24周前的早产(PTB)情况。

结果

两针组的平均分娩孕周显著大于一针组(32.71±5.54周 vs 27.99±4.70周,P = 0.028)。两针组在<34周和<32周时的自发性PTB发生率显著降低(分别为P = 0.034;P = 0.013)。两针组的新生儿重症监护病房(NICU)收治率和在NICU的住院时间显著降低(分别为P = 0.035和P = 0.018)。然而,两组之间的新生儿死亡率无显著差异。

结论

与一针紧急宫颈环扎术相比,两针手术能更有效地延长孕周并改善新生儿预后。

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