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The T-Cell Response to SARS-CoV-2 Vaccination in Inflammatory Bowel Disease is Augmented with Anti-TNF Therapy.

作者信息

Li Dalin, Xu Alexander, Mengesha Emebet, Elyanow Rebecca, Gittelman Rachel M, Chapman Heidi, Prostko John C, Frias Edwin C, Stewart James L, Pozdnyakova Valeriya, Debbas Philip, Mujukian Angela, Horizon Arash A, Merin Noah, Joung Sandy, Botwin Gregory J, Sobhani Kimia, Figueiredo Jane C, Cheng Susan, Kaplan Ian M, McGovern Dermot P B, Merchant Akil, Melmed Gil Y, Braun Jonathan

机构信息

F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

出版信息

Inflamm Bowel Dis. 2022 Jul 1;28(7):1130-1133. doi: 10.1093/ibd/izac071.

DOI:10.1093/ibd/izac071
PMID:35397000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9047232/
Abstract
摘要

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本文引用的文献

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Lower Serologic Response to COVID-19 mRNA Vaccine in Patients With Inflammatory Bowel Diseases Treated With Anti-TNFα.抗 TNF-α 治疗的炎症性肠病患者对 COVID-19 mRNA 疫苗的血清学反应较低。
Gastroenterology. 2022 Feb;162(2):454-467. doi: 10.1053/j.gastro.2021.10.029. Epub 2021 Oct 28.
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Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19.肿瘤坏死因子抑制剂与 COVID-19 合并免疫介导的炎症性疾病患者住院或死亡风险的相关性。
JAMA Netw Open. 2021 Oct 1;4(10):e2129639. doi: 10.1001/jamanetworkopen.2021.29639.
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新型冠状病毒肺炎与炎症性肠病实用最新进展:新型冠状病毒肺炎疾病风险及疫苗安全性与有效性
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Higher and Sustained Cell-Mediated Immune Responses After 3 Doses of mRNA COVID-19 Vaccine in Patients With Inflammatory Bowel Disease on Anti-Tumor Necrosis Factor Therapy.接受抗肿瘤坏死因子治疗的炎症性肠病患者接种3剂mRNA新冠疫苗后产生更高且持续的细胞介导免疫反应。
Clin Transl Gastroenterol. 2024 Apr 1;15(4):e00688. doi: 10.14309/ctg.0000000000000688.
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COVID-19 vaccination in adults with inflammatory bowel disease.炎症性肠病成年患者的新冠病毒疫苗接种
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Anti-tumor necrosis factor therapy is associated with attenuated humoral response to SARS-COV-2 vaccines in patients with inflammatory bowel disease.抗肿瘤坏死因子治疗与炎症性肠病患者对 SARS-CoV-2 疫苗的体液免疫应答减弱相关。
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炎症性肠病成年患者接种SARS-CoV-2 mRNA疫苗后的抗体反应
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