定义澳大利亚新南威尔士州沿海地区皮肤鳞状细胞癌的发病率。
Defining the incidence of cutaneous squamous cell carcinoma in coastal NSW Australia.
机构信息
Division of Surgery, Wollongong Hospital, Wollongong, Australia.
School of Medicine, University of New South Wales, Sydney, Australia.
出版信息
Australas J Dermatol. 2022 May;63(2):213-216. doi: 10.1111/ajd.13830. Epub 2022 Apr 9.
BACKGROUND/OBJECTIVES: To describe the incidence of primary cutaneous squamous cell carcinoma in coastal NSW Australia.
METHODS
The design is a case-controlled study of reported cSCC from 2016 to 2019 within a defined region of coastal southern NSW. Participants include all reported pathological diagnoses of cSCC in patients greater than 20 years of age. The main outcome measures the incidence and relative risk of cSCC.
RESULTS
The age-adjusted incidence rate of primary cSCC was 856/10 /year. Men over 60 years of age had an age-adjusted incidence rate of 2875/10 /year. Histologically diagnosed invasive SCC samples were included using SNOMED clinical term codes. Keratoacanthomas and SCC in situ SNOWMED codes were not included. SCC in situ results was found within the sample analysis and was offset by including one SCC per annum per person.
CONCLUSIONS
The rates of cSCC are far higher than previously reported and demand a reappraisal of our national management of this disease.
背景/目的：描述澳大利亚新南威尔士州沿海地区原发性皮肤鳞状细胞癌的发病率。
方法
本设计是对 2016 年至 2019 年在新南威尔士州南部沿海地区定义区域内报告的 cSCC 的病例对照研究。参与者包括所有年龄大于 20 岁的患者的病理诊断为 cSCC 的报告病例。主要观察指标为 cSCC 的发病率和相对风险。
结果
原发性 cSCC 的年龄调整发病率为 856/10 /年。60 岁以上男性的年龄调整发病率为 2875/10 /年。使用 SNOMED 临床术语代码纳入组织学诊断为侵袭性 SCC 的样本。未包括角化棘皮瘤和 SCC 原位 SNOWMED 代码。在样本分析中发现了 SCC 原位结果，并通过每年每人包括一个 SCC 进行了校正。
结论
cSCC 的发病率远高于以往报道，需要重新评估我们对这种疾病的全国管理。
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