Discipline of Ophthalmology and Visual Science, University of Adelaide, Adelaide, SA, Australia.
Department of Ophthalmology, Royal Adelaide Hospital and South Australian Institute of Ophthalmology, Adelaide, SA, Australia.
Eye (Lond). 2023 Mar;37(4):760-763. doi: 10.1038/s41433-022-02048-9. Epub 2022 Apr 9.
To ascertain the success of endo-DCR in nasolacrimal duct stenosis (NLDS) versus nasolacrimal duct obstruction (NLDO).
Consecutive adult patients with epiphora attending a tertiary lacrimal clinic from February 2012 to February 2021 were reviewed. NLDS was diagnosed by patent lacrimal syringing and combined dacryocystography (NLD stenosis) and dacryoscintigraphy (post-sac delay) findings in all eyes. Cases with evidence of canalicular stenosis or other identifiable causes of epiphora were excluded. The epiphora resolution and improvement rates following endo-DCR were compared between NLDS and complete NLDO cases.
DCRs in 24 NLDS (23 patients, 69.6% females, mean age 61.0 ± 17.07) and 58 NLDO (56 patients, 69.6% females, mean age 61.9 ± 17.4) were included. Resolution of epiphora was achieved in 10 (41.7% [95% CI 0.24-0.61]) of the NLDS cases compared to 40 (69.0% [95% CI 0.56-0.79]) in NLDO (p = 0.021). Improvement of epiphora (i.e., either improvement or resolution) was noted in 17 (70.8% [95% CI 0.51-0.85]) of NLDS and 53 (91.4% [95% CI 0.81-0.96]) of NLDO cases (p = 0.034). Three patients (12.5%) with NLDS had subsequent lacrimal procedures (one DCR revision, two Jones tube) at a median of 14 (range 11-21) months. 71.4% of the NLDS patients responded to a phone questionnaire at a median of 93 months postoperatively. Of these, 46.7% reported resolution or significant improvement, and 33.3% reported slight improvement. 64.3% said they would recommend DCR to others suffering from epiphora.
Endo-DCR may benefit approximately 70% of patients with NLDS. The success of endo-DCR in complete NLDO may be higher.
确定鼻内泪囊鼻腔吻合术(endo-DCR)治疗鼻泪管狭窄(NLDS)与鼻泪管阻塞(NLDO)的成功率。
回顾 2012 年 2 月至 2021 年 2 月在一家三级泪液诊所就诊的连续患有溢泪的成年患者。所有患者均通过泪道冲洗和联合泪囊造影(NLD 狭窄)和泪闪烁显像(囊后延迟)发现诊断为 NLDS。排除有泪小管狭窄或其他明确溢泪原因的病例。比较 NLDS 和完全 NLDO 病例 endo-DCR 后溢泪缓解和改善率。
共纳入 24 例 NLDS(23 例患者,女性占 69.6%,平均年龄 61.0±17.07 岁)和 58 例 NLDO(56 例患者,女性占 69.6%,平均年龄 61.9±17.4 岁)。NLDS 病例中,10 例(41.7%[95%CI 0.24-0.61])的溢泪得到缓解,而 NLDO 病例中 40 例(69.0%[95%CI 0.56-0.79])得到缓解(p=0.021)。NLDS 中有 17 例(70.8%[95%CI 0.51-0.85])和 NLDO 中有 53 例(91.4%[95%CI 0.81-0.96])的溢泪得到改善(即改善或缓解)(p=0.034)。NLDS 中有 3 例(12.5%)患者在中位时间为 14 个月(范围为 11-21 个月)时接受了其他泪道手术(1 例 DCR 翻修,2 例 Jones 管)。NLDS 患者中有 71.4%在术后中位时间为 93 个月时通过电话问卷调查做出回应。其中,46.7%的患者报告缓解或明显改善,33.3%的患者报告略有改善。64.3%的患者表示他们会向其他患有溢泪的患者推荐 DCR。
endo-DCR 可能使大约 70%的 NLDS 患者受益。endo-DCR 治疗完全 NLDO 的成功率可能更高。