Teoh Chia Yaw, Saravanamuthu Kavitha, Abdul Razak Zulhilmi, W Md Kasim Wan Mariny
Ophthalmology, International Islamic University of Medicine (IIUM), Kuantan, MYS.
Ophthalmology/Oculoplasty, Hospital Serdang, Kajang, MYS.
Cureus. 2024 Nov 27;16(11):e74565. doi: 10.7759/cureus.74565. eCollection 2024 Nov.
This study aims to determine the outcomes of probing and external dacryocystorhinostomy (exDCR) for congenital nasolacrimal duct obstruction (cNLDO) and the factors influencing the success rates in pediatric cNLDO.
A retrospective sample collection was conducted at the oculoplastic referral center over 10 years (January 2012 to December 2022) for cNLDO patients who had undergone probing or exDCR.
Data were retrospectively reviewed for patients aged ≤18 years who underwent probing or exDCR. Variables namely demographics, clinical presentations, indications for surgery, complications, and surgical outcomes were collected for further interpretation. Success was defined as the improvement of symptoms and resolution of clinical signs after at least six months of follow-up. Logistic regression was performed to analyze factors affecting success rates.
A total of 109 patients were included (66 exDCR, 43 probing), with nearly similar male-to-female distribution. Common presentations were epiphora and mucous discharge. The majority of cases were simple cNLDO (91% in the probing group, 88% in the exDCR group). Indications for surgery were dacryocystitis, fistula, canaliculitis, and persistent symptoms despite Crigler massage. The success rates were 60.5% for probing and 86.4% for exDCR. Complications varied between procedures and included fistula, tube dislodgement, and granuloma formation. Younger age and the absence of dacryocystitis were significantly associated with higher success rates in probing. Other factors influencing success rates, included simple cNLDO, bilaterality, and the use of endoscopic guidance despite non-significance statistically.
The success rates for probing and exDCR were 60.5% and 86.4%, respectively. Statistically significant factors associated with improved outcomes included younger age and the absence of dacryocystitis. Other factors, such as simple cNLDO, bilaterality of disease, and endoscopic guidance, may also contribute to better outcomes, though they were not statistically significant.
本研究旨在确定先天性鼻泪管阻塞(cNLDO)行泪道探通术和外路泪囊鼻腔吻合术(exDCR)的治疗效果,以及影响小儿cNLDO成功率的因素。
在眼科整形转诊中心进行了一项为期10年(2012年1月至2022年12月)的回顾性样本收集,纳入接受泪道探通术或exDCR的cNLDO患者。
对年龄≤18岁接受泪道探通术或exDCR的患者数据进行回顾性分析。收集人口统计学、临床表现、手术指征、并发症和手术结果等变量以作进一步解读。成功定义为随访至少6个月后症状改善且临床体征消失。进行逻辑回归分析影响成功率的因素。
共纳入109例患者(66例行exDCR,43例行泪道探通术),男女分布相近。常见表现为溢泪和黏液分泌物。大多数病例为单纯性cNLDO(泪道探通术组91%,exDCR组88%)。手术指征为泪囊炎、瘘管、泪小管炎以及尽管进行了克里格勒按摩仍有持续症状。泪道探通术成功率为60.5%,exDCR成功率为86.4%。并发症因手术方式而异,包括瘘管、置管移位和肉芽肿形成。年龄较小且无泪囊炎与泪道探通术较高的成功率显著相关。其他影响成功率的因素包括单纯性cNLDO、双侧病变以及使用内镜引导,尽管在统计学上无显著意义。
泪道探通术和exDCR的成功率分别为60.5%和86.4%。与改善预后相关的具有统计学意义的因素包括年龄较小和无泪囊炎。其他因素,如单纯性cNLDO、疾病双侧性和内镜引导,也可能有助于取得更好的结果,尽管它们在统计学上不显著。