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巨细胞动脉炎合并急性 Q 热——1 例报告。

Giant cell arteritis associated with acute Q fever - A case report.

机构信息

3rd Internal Medicine Department, Red Cross General Hospital of Athens "Korgialenio-Benakio", Athens, Greece.

3rd Internal Medicine Department, Red Cross General Hospital of Athens "Korgialenio-Benakio", Athens, Greece.

出版信息

J Infect Chemother. 2022 Aug;28(8):1177-1179. doi: 10.1016/j.jiac.2022.03.028. Epub 2022 Apr 6.

DOI:10.1016/j.jiac.2022.03.028
PMID:35397975
Abstract

Q fever is a worldwide spread zoonotic disease, caused by the gram-negative intracellular bacillus Coxiella burnetii. Apart from its most common manifestations, Q fever has been reported to occasionally mimic autoimmune diseases. We herein present a case of acute Q fever in a 69-year-old man, manifesting as prolonged fever with pneumonitis, in whom biopsy of the temporal artery revealed giant cell arteritis. Moreover, PCR testing of the biopsy specimen was positive for Coxiella burnetii, thus further supporting the possibly infectious etiology of some cases of biopsy proven giant cell arteritis, with implications for treatment.

摘要

Q 热是一种广泛传播的人畜共患病,由革兰氏阴性细胞内杆菌柯克斯体引起。除了最常见的表现外,Q 热偶尔也会模仿自身免疫性疾病。本文报道了一例 69 岁男性急性 Q 热,表现为持续性发热伴肺炎,颞动脉活检显示巨细胞动脉炎。此外,活检标本的 PCR 检测为柯克斯体阳性,进一步支持活检证实的巨细胞动脉炎的某些病例可能具有传染性病因,并对治疗具有影响。

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