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软骨移植——现状

Cartilage grafts--present status.

作者信息

Zalzal G H, Cotton R T, McAdams A J

出版信息

Head Neck Surg. 1986 May-Jun;8(5):363-74. doi: 10.1002/hed.2890080507.

Abstract

Cartilage grafts have been in use for almost a century and have proved their usefulness. Many questions about immunology, survival, growth, and role of perichondrium are still debated. We are presenting a review of the literature and of our experimental work on cartilage grafts. Ear cartilage was transplanted from 28 young New Zealand rabbits subcutaneously in the chest walls. The grafts were divided into 1) bare cartilage, 2) perichondrium, 3) cartilage covered with perichondrium on one side, and 4) cartilage covered with perichondrium on both sides. The grafts were measured in length and weight before transplantation, and at 2 and 4 months after transplantation; they were compared to a control piece of cartilage tagged in situ. Histologic examination was performed on all retrieved grafts. Transplanted cartilage survival was good in over 75% of cases; however, cartilage production from perichondrium was minimal and no growth was noticed in any of the grafts.

摘要

软骨移植已经应用了近一个世纪,并且已经证明了其有效性。许多关于免疫学、存活、生长以及软骨膜作用的问题仍在争论中。我们正在对软骨移植的文献和我们的实验工作进行综述。从28只年轻的新西兰兔身上取下耳软骨,皮下移植到胸壁。移植的软骨分为1)裸软骨,2)软骨膜,3)一侧覆盖软骨膜的软骨,4)两侧覆盖软骨膜的软骨。在移植前、移植后2个月和4个月测量移植软骨的长度和重量;将其与原位标记的对照软骨片进行比较。对所有回收的移植软骨进行组织学检查。超过75%的病例中移植软骨存活良好;然而,软骨膜产生的软骨极少,并且在任何移植软骨中均未观察到生长。

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