Department of Dermatology, Xi'an Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi 710021, China.
Department of Second Surgery, Gushi County Hospital of Traditional Chinese Medicine, Xinyang, Henan 465200, China.
Comput Math Methods Med. 2022 Mar 3;2022:7202626. doi: 10.1155/2022/7202626. eCollection 2022.
Both traditional Chinese medicine (TCM) and Western medicine are widely applied in the treatment of eczema, but there are few reports on integrated TCM and Western medicine for eczema.
This meta-analysis carried out the evaluation on the efficacy of integrated TCM and Western medicine in the treatment of eczema.
PubMed, Web of Science, Embase, CNKI, and Wanfang databases were searched for all possible randomized controlled trials from 2000 to 2021. A meta-analysis of the included studies was also performed using Stata16 software.
A total of 16 studies including 1946 patients were included. Compared with the control group, the pooled results of the 16 studies showed that effective rate in the treatment group was higher (OR = 4.50, 95% CI: 3.16-6.40, < 0.05), and the pooled data of 15 studies revealed that the cure rate was increased in the treatment group (OR = 2.60, 95% CI: 2.13-3.18, < 0.05). Additionally, compared with the control group, pooled data of 11 studies demonstrated that lesion area after treatment was reduced in the treatment group (SMD = -1.91; 95% CI: -2.51, -1.31; < 0.05), and pooled data of 9 studies showed that the degree of pruritus after treatment in the treatment group was lower (SMD = -1.69; 95% CI: -2.07, -1.30; < 0.05).
In comparison with Western medicine alone, integrated TCM and Western medicine are a more effective treatment for eczema, which can not only significantly improve the effective rate and cure rate but also reduce the lesion area and degree of pruritus.
中医和西医在湿疹的治疗中均有广泛应用，但有关中西医结合治疗湿疹的报道较少。
本研究旨在对中西医结合治疗湿疹的疗效进行评价。
检索 2000 年至 2021 年PubMed、Web of Science、Embase、中国知网和万方数据库中所有可能的随机对照试验，采用 Stata16 软件对纳入的研究进行荟萃分析。
共纳入 16 项研究，包括 1946 例患者。与对照组相比，16 项研究的汇总结果显示，治疗组的有效率更高（OR=4.50，95%CI：3.16-6.40， < 0.05），15 项研究的汇总数据显示治疗组的治愈率增加（OR=2.60，95%CI：2.13-3.18， < 0.05）。此外，与对照组相比，11 项研究的汇总数据显示治疗后皮损面积减小（SMD=-1.91；95%CI：-2.51，-1.31； < 0.05），9 项研究的汇总数据显示治疗后瘙痒程度降低（SMD=-1.69；95%CI：-2.07，-1.30； < 0.05）。
与单纯西医治疗相比，中西医结合治疗湿疹更为有效，不仅能显著提高有效率和治愈率，还能减轻皮损面积和瘙痒程度。
