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经皮椎体成形术(PVP)与经皮椎体后凸成形术(PKP)联合三联药物治疗老年轻度和中度骨质疏松性椎体压缩骨折的疗效比较

Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly.

作者信息

Zhou Yi, Jiang Jiang, Gu Fulong, Mi Daguo

机构信息

Department of Orthopedics and Traumatology, Nantong Hospital of Traditional Chinese Medicine, Affiliated Traditional Chinese Medicine Hospital of Nantong University, Nantong, China.

出版信息

Front Surg. 2022 Mar 25;8:663099. doi: 10.3389/fsurg.2021.663099. eCollection 2021.

DOI:10.3389/fsurg.2021.663099
PMID:35402473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8990093/
Abstract

OBJECTIVE

To compare and analyze the therapeutic effect of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) combined with triple therapy on elderly patients with mild to moderate osteoporotic vertebral compression fractures (OVCF).

METHODS

A total of 114 cases of elderly patients with mild to moderate osteoporotic vertebral compression fractures were identified as research subjects in our hospital from January 2017 to January 2018, and a total of 136 vertebrae were included. The patients who underwent PVP operation were included as the control group with 67 injured vertebrae, and the patients who underwent PKP operation were included as the experimental group with 69 injured vertebrae.

RESULTS

The operation time and bone cement injection volume of the experimental group were significantly higher than the control group. The visual analog scale (VAS) scores of the two groups at 3 months and 6 months after operation were lower than those before operation, with lower VAS scores observed in the experimental group at 3 months and 6 months after operation. The anterior height of the vertebral body in the experimental group was higher than that of the control group. The experimental group outperformed the control group in the incidence of postoperative complications. The postoperative Oswestry dysfunction index (ODI) scores of the two groups were lower before the operation, in which the experimental group had lower scores than the control group ( < 0.05).

CONCLUSION

PVP and PKP combined with postoperative triple therapy can achieve a promising analgesic effect. PKP has a higher volume of bone cement injection volume, and a lower incidence of complications, which gives rise to a better vertebral body recovery height than that of PVP, with rapid postoperative body function recovery and good quality of life.

摘要

目的

比较和分析经皮椎体成形术(PVP)与经皮后凸成形术(PKP)联合三联疗法对老年轻中度骨质疏松性椎体压缩骨折(OVCF)的治疗效果。

方法

选取2017年1月至2018年1月我院收治的114例老年轻中度骨质疏松性椎体压缩骨折患者作为研究对象,共纳入136个椎体。接受PVP手术的患者作为对照组,有67个受伤椎体;接受PKP手术的患者作为实验组,有69个受伤椎体。

结果

实验组的手术时间和骨水泥注入量均显著高于对照组。两组术后3个月和6个月的视觉模拟评分(VAS)均低于术前,且实验组术后3个月和6个月的VAS评分更低。实验组椎体前缘高度高于对照组。实验组术后并发症发生率低于对照组。两组术后Oswestry功能障碍指数(ODI)评分均低于术前,其中实验组评分低于对照组(<0.05)。

结论

PVP和PKP联合术后三联疗法可取得良好的镇痛效果。PKP骨水泥注入量更大,并发症发生率更低,椎体恢复高度优于PVP,术后身体功能恢复快,生活质量良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23a/8990093/f0756546b1a7/fsurg-08-663099-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23a/8990093/c9750c8e0c20/fsurg-08-663099-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23a/8990093/6c93e4ceaa6d/fsurg-08-663099-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23a/8990093/f0756546b1a7/fsurg-08-663099-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23a/8990093/c9750c8e0c20/fsurg-08-663099-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23a/8990093/6c93e4ceaa6d/fsurg-08-663099-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23a/8990093/f0756546b1a7/fsurg-08-663099-g0003.jpg

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