不同屈光不正患者虹膜血管和血流的定量变化。
Quantitative changes in iris vasculature and blood flow in patients with different refractive errors.
机构信息
Department of Ophthalmology, Shanghai General Hospital Affiliated Nanjing Medical University, Shanghai, China.
Department of Ophthalmology, Changzhou Second People's Hospital Affiliated Nanjing Medical University, Changzhou, China.
出版信息
Graefes Arch Clin Exp Ophthalmol. 2022 Sep;260(9):3123-3129. doi: 10.1007/s00417-022-05632-7. Epub 2022 Apr 11.
PURPOSE
To evaluate the association between microvascular changes in the iris and refractive errors.
METHODS
A cross-sectional case study. Seventy eyes from 70 patients with refractive errors were enrolled. Iris microvasculature was analyzed using optical coherence tomography angiography (OCTA). We divided the iris images into three regions and calculated the vessel area density (VAD) and vessel skeleton density (VSD) of the inner one-third, inner two-thirds, and the entirety of the iris.
RESULTS
The VADs and VSDs of the different regions were significantly different. The VAD and VSD of the inner one-third of the iris were higher than those of the other regions. The iris blood vessels were denser near the pupil margin, and blood vessels from the iris root to the pupil edge were radially distributed. The VAD and VSD of patients with mild hyperopia and emmetropia were higher than those of patients with moderate and high myopia. As the spherical equivalent increased, the VAD and VSD of the iris increased. Neither age nor sex contributed to significant differences in VAD and VSD.
CONCLUSION
Quantitative changes in iris microvasculature may indicate the development of myopia.
目的
评估虹膜微血管变化与屈光不正的关系。
方法
横断面病例研究。纳入 70 例屈光不正患者的 70 只眼。使用光学相干断层扫描血管造影术（OCTA）分析虹膜微血管。我们将虹膜图像分为三个区域，并计算内三分之一、内三分之二和整个虹膜的血管面积密度（VAD）和血管骨架密度（VSD）。
结果
不同区域的 VAD 和 VSD 存在显著差异。虹膜内三分之一的 VAD 和 VSD 高于其他区域。虹膜血管在瞳孔缘附近更密集，从虹膜根部到瞳孔边缘的血管呈放射状分布。轻度远视和正视患者的 VAD 和 VSD 高于中度和高度近视患者。随着球镜等效的增加，虹膜的 VAD 和 VSD 增加。年龄和性别均与 VAD 和 VSD 无显著差异。
结论
虹膜微血管的定量变化可能表明近视的发展。
Zotero 插件