圈养虎血清和血浆中类固醇和甲状腺激素浓度的比较。
Comparison of steroid and thyroid hormone concentrations in blood serum and plasma of captive tigers.
机构信息
Department of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, TN, USA.
Small Animal Clinical Sciences, University of Tennessee, Knoxville, TN, USA.
出版信息
J Vet Diagn Invest. 2022 May;34(3):547-551. doi: 10.1177/10406387221090538. Epub 2022 Apr 11.
Analysis of steroid and thyroid hormones is often performed in blood serum. Occasionally though, plasma samples are submitted in lieu of serum for exotic species such as tigers. However, blood tube anticoagulants may affect hormone values. We compared serum and heparin plasma results for 7 hormones in tigers. Serum and plasma samples were collected from 25 tigers and analyzed for progesterone, 17-hydroxyprogesterone, cortisol, androstenedione, testosterone, estradiol, and thyroxine. Using Lin concordance correlation, serum and heparin plasma measures agreed for all hormones except cortisol. However, Passing-Bablok regression only found agreement between serum and heparin plasma measures for androstenedione, testosterone, and estradiol. Median values between the 2 sample types were significantly ( < 0.05) different for progesterone, 17-hydroxyprogesterone, cortisol, and thyroxine. Our results suggest that, for the aforementioned hormones, serum and heparin plasma values may not always be comparable.
类固醇和甲状腺激素的分析通常在血清中进行。但偶尔也会提交血浆样本代替血清，用于研究老虎等特殊物种。然而，血液管抗凝剂可能会影响激素值。我们比较了 7 种激素在老虎血清和肝素血浆中的结果。从 25 只老虎中采集血清和血浆样本，分析孕酮、17-羟孕酮、皮质醇、雄烯二酮、睾酮、雌二醇和甲状腺素。使用 Lin 一致性相关分析，血清和肝素血浆测量结果在所有激素中均一致，除皮质醇外。然而，Passing-Bablok 回归仅发现雄烯二酮、睾酮和雌二醇的血清和肝素血浆测量结果之间存在一致性。这两种样本类型的中位数差异在孕酮、17-羟孕酮、皮质醇和甲状腺素方面具有统计学意义（<0.05）。我们的结果表明，对于上述激素，血清和肝素血浆值可能并不总是具有可比性。
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