Light K, Van Blerk P J
S Afr Med J. 1978 Apr 15;53(15):584-6.
Primary vesico-ureteric reflux must be graded according to severity. Significant reflux up a dilated ureter appears to be an important factor in causing renal damage. There is evidence in favour of the theory that the renal deterioration seen in some cases of reflux can be explained on a congenital basis of site or origin of the ureteral bud and resultant dysplasia of the developing kidney. Surgery should be reserved for selected patients with significant reflux.
原发性膀胱输尿管反流必须根据严重程度进行分级。尿液沿扩张的输尿管向上的显著反流似乎是导致肾损伤的一个重要因素。有证据支持这样一种理论，即反流某些病例中出现的肾脏恶化可以用输尿管芽的部位或起源的先天性基础以及发育中的肾脏由此产生的发育异常来解释。手术应仅适用于有显著反流的特定患者。
