Pediatric Hematology/Oncology, Rainbow Babies and Children's Hospital, Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Department of Plastic and Oral Surgery, Lymphedema Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Pediatr Blood Cancer. 2022 Aug;69(8):e29611. doi: 10.1002/pbc.29611. Epub 2022 Apr 11.
Lymphedema in children is rare; however, it is usually a progressive and chronic condition. Accurate diagnosis of lymphedema in the pediatric population often takes several months and sometimes is delayed for years. Lymphedema can be isolated or associated with genetic syndromes, thus it is very important to identify the correct diagnosis, to select carefully which patients to refer for genetic testing, and to initiate appropriate treatment in a timely fashion. In this article, we review key information about diagnosis of lymphedema, associated conditions and syndromes, and current treatment modalities.
儿童淋巴水肿较为罕见，但通常呈进行性和慢性发展。儿科人群中淋巴水肿的准确诊断通常需要数月时间，有时甚至会延迟数年。淋巴水肿可能为孤立性疾病，也可能与遗传综合征相关，因此，明确正确的诊断、仔细选择需要进行基因检测的患者并及时开始适当的治疗非常重要。本文综述了淋巴水肿的诊断、相关病症和综合征以及当前治疗方法的关键信息。
