先天性血管和淋巴管疾病。
Congenital Vascular and Lymphatic Diseases.
机构信息
Division of Cardiovascular Medicine (R.J., C.M.T.), UMass Chan Medical School; Worcester.
Department of Medicine (R.J., C.M.T.), UMass Chan Medical School; Worcester.
出版信息
Circ Res. 2024 Jun 21;135(1):159-173. doi: 10.1161/CIRCRESAHA.124.323181. Epub 2024 Jun 20.
Abstract
Over the past several centuries, the integration of contemporary medical techniques and innovative technologies, like genetic sequencing, have played a pivotal role in enhancing our comprehension of congenital vascular and lymphatic disorders. Nonetheless, the uncommon and complex characteristics of these disorders, especially considering their formation during the intrauterine stage, present significant obstacles in diagnosis and treatment. Here, we review the intricacies of these congenital abnormalities, offering an in-depth examination of key diagnostic approaches, genetic factors, and therapeutic methods.
摘要
在过去的几个世纪中，当代医学技术与创新技术（如基因测序）的融合，在增强我们对先天性血管和淋巴管疾病的理解方面发挥了关键作用。然而，这些疾病的罕见和复杂特征，特别是考虑到它们在宫内阶段形成时，给诊断和治疗带来了重大障碍。在这里，我们回顾了这些先天性异常的复杂性，深入探讨了关键的诊断方法、遗传因素和治疗方法。
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