• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

细菌性脑膜炎后听力损失的回顾性研究

Hearing loss after bacterial meningitis, a retrospective study.

作者信息

Persson Filip, Bjar Nora, Hermansson Ann, Gisselsson-Solen Marie

机构信息

Lund University Hospital, Lund, Sweden.

Department of Otorhinolaryngology, Head and Neck Surgery, Skåne University Hospital, Lund, Sweden.

出版信息

Acta Otolaryngol. 2022 Mar-Apr;142(3-4):298-301. doi: 10.1080/00016489.2022.2058708. Epub 2022 Apr 11.

DOI:10.1080/00016489.2022.2058708
PMID:35404758
Abstract

BACKGROUND

Hearing loss is a common sequela after bacterial meningitis, but risk factors for this are poorly studied, particularly in relation to concurrent acute otitis media (AOM).

AIMS

The aim of this study was to investigate incidence and risk factors for hearing loss in patients treated for bacterial meningitis.

METHODS

In this retrospective study, medical records for patients admitted to hospital with bacterial meningitis in Skåne county, Sweden, between 2000 and 2017 were retrieved. The association between risk factors and hearing loss was estimated using logistic regression.

RESULTS

During the 18 years, 187 cases of meningitis were identified. Hearing loss was confirmed in 71 of the 119 patients who had done an audiometry. It was significantly more common in adults. There was also evidence of an association between hearing loss and AOM, and between hearing loss and pneumococcal infection.

CONCLUSION

Age, concurrent AOM and pneumococcal infection were risk factors for developing hearing loss. Despite being recommended in the national guidelines, more than a third of the patients had not done a hearing test after recovering from bacterial meningitis. The findings strengthen the demand for prompt ear examination and - if needed - tympanocentesis in meningitis patients.

摘要

背景

听力损失是细菌性脑膜炎后的常见后遗症,但对此的危险因素研究较少,尤其是与并发急性中耳炎(AOM)相关的因素。

目的

本研究旨在调查接受细菌性脑膜炎治疗的患者听力损失的发生率和危险因素。

方法

在这项回顾性研究中,检索了2000年至2017年期间瑞典斯科讷郡因细菌性脑膜炎入院患者的病历。使用逻辑回归估计危险因素与听力损失之间的关联。

结果

在这18年中,共确诊187例脑膜炎病例。119例进行听力测试的患者中,71例被确诊有听力损失。在成人中更为常见。也有证据表明听力损失与AOM之间以及听力损失与肺炎球菌感染之间存在关联。

结论

年龄、并发AOM和肺炎球菌感染是发生听力损失的危险因素。尽管国家指南中有相关推荐,但超过三分之一的患者在从细菌性脑膜炎康复后未进行听力测试。这些发现强化了对脑膜炎患者进行及时耳部检查以及(如有需要)鼓膜穿刺术的需求。

相似文献

1
Hearing loss after bacterial meningitis, a retrospective study.细菌性脑膜炎后听力损失的回顾性研究
Acta Otolaryngol. 2022 Mar-Apr;142(3-4):298-301. doi: 10.1080/00016489.2022.2058708. Epub 2022 Apr 11.
2
How common is otogenic meningitis? A retrospective study in southern Sweden over 18 years.耳源性脑膜炎有多常见?瑞典南部 18 年回顾性研究。
Infection. 2024 Aug;52(4):1377-1384. doi: 10.1007/s15010-024-02195-z. Epub 2024 Feb 28.
3
Acute otitis media in infants younger than two months of age: Epidemiologic and microbiologic characteristics in the era of pneumococcal conjugate vaccines.两个月以下婴儿的急性中耳炎:肺炎球菌结合疫苗时代的流行病学和微生物学特征
Int J Pediatr Otorhinolaryngol. 2019 Apr;119:123-130. doi: 10.1016/j.ijporl.2019.01.031. Epub 2019 Jan 23.
4
[Characteristics and recovery of hearing loss in 573 patients with bacterial meningitis].[573例细菌性脑膜炎患者听力损失的特征及恢复情况]
Zhonghua Er Ke Za Zhi. 2021 Aug 2;59(8):633-639. doi: 10.3760/cma.j.cn112140-20210511-00409.
5
Increased Risk of Long-Term Disabilities Following Childhood Bacterial Meningitis in Sweden.瑞典儿童细菌性脑膜炎后长期残疾风险增加。
JAMA Netw Open. 2024 Jan 2;7(1):e2352402. doi: 10.1001/jamanetworkopen.2023.52402.
6
Bacterial etiology of acute otitis media in the era prior to universal pneumococcal vaccination in Taiwanese children.台湾儿童在普遍进行肺炎球菌疫苗接种之前,急性中耳炎的细菌病因。
J Microbiol Immunol Infect. 2014 Jun;47(3):239-44. doi: 10.1016/j.jmii.2013.08.016. Epub 2013 Sep 27.
7
Pediatric Acute Otitis Media in the Era of Pneumococcal Vaccination.肺炎球菌疫苗时代的小儿急性中耳炎
Otolaryngol Head Neck Surg. 2017 May;156(5):938-945. doi: 10.1177/0194599817699599. Epub 2017 Mar 28.
8
Inner ear and facial nerve complications of acute otitis media with focus on bacteriology and virology.急性中耳炎的内耳及面神经并发症,重点关注细菌学和病毒学
Acta Otolaryngol. 2006 May;126(5):460-6. doi: 10.1080/00016480500401043.
9
Otitis media as a cause of significant hearing loss among Nigerians.中耳炎是尼日利亚人严重听力丧失的一个原因。
Int J Pediatr Otorhinolaryngol. 2008 Jun;72(6):787-92. doi: 10.1016/j.ijporl.2008.02.008. Epub 2008 Apr 2.
10
Incidence of Inner Ear Disorders in Various Forms of Acute Otitis Media in ENT Practices in Germany.德国耳鼻喉科诊所中各种形式急性中耳炎的内耳疾病发病率。
Ear Nose Throat J. 2021 Jun;100(3_suppl):325S-332S. doi: 10.1177/0145561320930568. Epub 2020 Jun 24.

引用本文的文献

1
Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages.小鼠内耳组织的冷冻切片和免疫染色:从胚胎期到成年期
J Vis Exp. 2025 Apr 11(218). doi: 10.3791/67647.
2
Neurological sequelae after childhood bacterial meningitis.儿童细菌性脑膜炎后的神经后遗症。
Eur J Pediatr. 2024 Dec;183(12):5203-5212. doi: 10.1007/s00431-024-05788-w. Epub 2024 Sep 30.
3
Comparative Histopathologic Analysis of Inner Ear Damage in Meningitis: Otogenic Versus Meningogenic Routes.脑膜炎内耳损伤的比较组织病理学分析:耳源性与脑膜源性途径
Laryngoscope. 2025 Feb;135(2):864-872. doi: 10.1002/lary.31759. Epub 2024 Sep 12.
4
Exploring Inner Ear and Brain Connectivity through Perilymph Sampling for Early Detection of Neurological Diseases: A Provocative Proposal.通过外淋巴采样探索内耳与脑的连通性以早期检测神经疾病:一项具有启发性的提议。
Brain Sci. 2024 Jun 20;14(6):621. doi: 10.3390/brainsci14060621.
5
Clinical research progress on intrathecal glucocorticoids in the treatment of infections: A review.鞘内糖皮质激素治疗感染的临床研究进展:综述。
Medicine (Baltimore). 2024 May 17;103(20):e38123. doi: 10.1097/MD.0000000000038123.
6
Cochlear Implants after Meningitis and Otosclerosis: A Comparison between Cochlear Ossification and Speech Perception Tests.脑膜炎和耳硬化症后的人工耳蜗植入:耳蜗骨化与言语感知测试的比较
J Pers Med. 2024 Apr 18;14(4):428. doi: 10.3390/jpm14040428.
7
How common is otogenic meningitis? A retrospective study in southern Sweden over 18 years.耳源性脑膜炎有多常见?瑞典南部 18 年回顾性研究。
Infection. 2024 Aug;52(4):1377-1384. doi: 10.1007/s15010-024-02195-z. Epub 2024 Feb 28.
8
Hearing Loss in Bacterial Meningitis Revisited-Evolution and Recovery.细菌性脑膜炎所致听力损失的再探讨——演变与恢复
Open Forum Infect Dis. 2023 Feb 4;10(3):ofad056. doi: 10.1093/ofid/ofad056. eCollection 2023 Mar.