Astvatsaturian M Z
Mol Gen Mikrobiol Virusol. 1986 May(5):35-8.
The suppression of temperature sensitive phenotype caused by mutation rho ts 15, making cells deficient in transcription termination, but mutation crp11 impairing the cAMP-receptor protein (cap) restores transcription termination on IS3 sequence in galactose operon and on the site before the promoter of udp gene in strains crp11 rho ts15. The obtained data suggest the direct interaction between factor Rho and cAMP-CAP complex in transcription process.
由rho ts 15突变引起的温度敏感表型的抑制,使细胞在转录终止方面存在缺陷,但crp11突变损害了cAMP受体蛋白(cap),这恢复了crp11 rho ts15菌株中半乳糖操纵子IS3序列上以及udp基因启动子之前位点的转录终止。所获得的数据表明在转录过程中因子Rho与cAMP-CAP复合物之间存在直接相互作用。