Molina-Rueda Francisco, Fernández-Vázquez Diego, Navarro-López Víctor, Miangolarra-Page Juan Carlos, Carratalá-Tejada María
Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine Department, Faculty of Health Sciences, Rey Juan Carlos University, 28922 Madrid, Spain.
Movement Analysis, Biomechanics, Ergonomics, and Motor Control Laboratory, Faculty of Health Sciences, Rey Juan Carlos University, 28922 Madrid, Spain.
J Clin Med. 2022 Mar 29;11(7):1892. doi: 10.3390/jcm11071892.
This study aimed to evaluate walking in multiple sclerosis (MS) patients with mild disability. A case control study with 8 mild disability MS patients and 10 controls was conducted. This study analyzed spatiotemporal, kinematic, and kinetic parameters. We also analyzed the timing of these parameters, as a percentage of the gait cycle. The MS patients and controls walked with a similar gait pattern. However, there were differences in the timing of the biomechanical parameters. The timing of toe-off was at 62-63% of gait cycle in MS subjects while in controls it was at 59.94% ( = 0.009 to 0.027 vs. to controls). The peak of knee flexion during swing was at 74-76% of gait cycle in MS subjects while in controls was at 72% ( = 0.027 to 0.034). While the peak of ankle dorsiflexion during stance occurred at 48-50% in MS subjects, while in controls it was at 46% ( = 0.001 to 0.009), and the peak of plantar flexion during pre-swing was at 66% in MS subjects vs. 64% in controls ( = 0.001). At the kinetic pattern, the first peak of the vertical ground reaction force occurred at 14% of gait cycle in controls while in MS patients it was at 17-20% ( = 0.012 to 0.021). MS subjects with mild disability walked with similar spatiotemporal parameters, joint angles and moments compared to controls. However, our results suggest that those changed the temporal occurrences, expressed as percentage of the gait cycle, of the kinematic and kinetic parameters.
本研究旨在评估轻度残疾的多发性硬化症（MS）患者的步行情况。开展了一项病例对照研究，纳入8例轻度残疾的MS患者和10名对照者。本研究分析了时空参数、运动学参数和动力学参数。我们还分析了这些参数出现的时间点，以步态周期的百分比表示。MS患者和对照者的步态模式相似。然而，生物力学参数出现的时间点存在差异。MS患者中足趾离地的时间点在步态周期的62%-63%，而对照者为59.94%（与对照者相比，P=0.009至0.027）。摆动期膝关节屈曲峰值在MS患者中出现在步态周期的74%-76%，而对照者为72%（P=0.027至0.034）。站立期踝关节背屈峰值在MS患者中出现在48%-50%，而对照者为46%（P=0.001至0.009），摆动前期跖屈峰值在MS患者中为66%，对照者为64%（P=0.001）。在动力学模式方面，垂直地面反作用力的第一个峰值在对照者中出现在步态周期的14%，而MS患者为17%-20%（P=0.012至0.021）。与对照者相比，轻度残疾的MS患者行走时的时空参数、关节角度和力矩相似。然而，我们的结果表明，运动学和动力学参数以步态周期百分比表示的时间出现情况发生了改变。
