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腹腔镜手术治疗轻中度小儿腹部创伤的疗效与安全性:一项系统评价和荟萃分析

Efficacy and Safety of Laparoscopy for Mild and Moderate Pediatric Abdominal Trauma: A Systematic Review and Meta-Analysis.

作者信息

Park Yun Chul, Jo Young Goun, Ki Young-Jun, Kang Wu Seong, Kim Joongsuck

机构信息

Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, Chonnam National University, Gwangju 61469, Korea.

Division of Acute Care Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

出版信息

J Clin Med. 2022 Mar 31;11(7):1942. doi: 10.3390/jcm11071942.

Abstract

In this systematic review and meta-analysis, we aimed to investigate the efficacy and safety of laparoscopy for pediatric patients with abdominal trauma. Relevant articles were obtained by searching the MEDLINE PubMed, EMBASE, and Cochrane databases until 7 December 2021. Meta-analyses were performed using odds ratio (OR) for binary outcomes, standardized mean differences (SMDs) for continuous outcome measures, and overall proportion for single proportional outcomes. Nine studies examining 12,492 patients were included in our meta-analysis. Our meta-analysis showed younger age (SMD -0.47, 95% confidence interval (CI) -0.52 to -0.42), lower injury severity score (SMD -0.62, 95% CI -0.67 to -0.57), shorter hospital stay (SMD -0.55, 95% CI -0.60 to -0.50), less complications (OR 0.375, 95% CI 0.309 to 0.455), and lower mortality rate (OR 0.055, 95% CI 0.0.28 to 0.109) in the laparoscopy group compared to the laparotomy group. The majority of patients were able to avoid laparotomy (0.816, 95% CI 0.800 to 0.833). There were no missed injuries during the laparoscopic procedures in seven eligible studies. Laparoscopy for stable pediatric patients showed favorable outcomes in terms of morbidity and mortality. There were no missed injuries, and laparotomy could be avoided for the majority of patients.

摘要

在这项系统评价和荟萃分析中,我们旨在研究腹腔镜手术治疗小儿腹部创伤患者的疗效和安全性。通过检索MEDLINE、PubMed、EMBASE和Cochrane数据库获取相关文章,检索截止至2021年12月7日。采用比值比(OR)对二元结局进行荟萃分析,采用标准化均数差(SMD)对连续结局指标进行分析,采用总体比例对单一比例结局进行分析。我们的荟萃分析纳入了9项研究,共涉及12492例患者。我们的荟萃分析显示,与开腹手术组相比,腹腔镜手术组患者年龄更小(SMD -0.47,95%置信区间(CI)-0.52至-0.42)、损伤严重程度评分更低(SMD -0.62,95% CI -0.67至-0.57)、住院时间更短(SMD -0.55,95% CI -0.60至-0.50)、并发症更少(OR 0.375,95% CI 0.309至0.455)、死亡率更低(OR 0.055,95% CI 0.028至0.109)。大多数患者能够避免开腹手术(0.816,95% CI 0.800至0.833)。在7项符合条件的研究中,腹腔镜手术过程中未出现漏诊损伤。对于病情稳定的小儿患者,腹腔镜手术在发病率和死亡率方面显示出良好的效果。没有漏诊损伤,并且大多数患者可以避免开腹手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef63/8999532/d00d0d0b71a3/jcm-11-01942-g001.jpg

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