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髌腱病——注射疗法有作用吗?随机对照试验的系统评价

Patellar Tendinopathy-Does Injection Therapy Have a Role? A Systematic Review of Randomised Control Trials.

作者信息

Nuhmani Shibili, Ahsan Mohammad, Bari Mohd Arshad, Malhotra Deepak, Al Muslem Wafa Hashem, Alsaadi Saad Mohammed, Muaidi Qassim Ibrahim

机构信息

Department of Physical Therapy, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.

Department of Physical Education, Aligarh Muslim University, Aligarh 202002, India.

出版信息

J Clin Med. 2022 Apr 3;11(7):2006. doi: 10.3390/jcm11072006.

DOI:10.3390/jcm11072006
PMID:35407614
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8999520/
Abstract

Injection treatment is one of the most widely used methods for the conservative management of patellar tendinopathy. The objective of this systematic review was to synthesise data from randomised control trails on the effectiveness of various injections used in the management of patellar tendinopathy. An electronic search was conducted in the Web of Science, Scopus, PubMed, and SPORTDiscus databases. To be included in the current systematic review, the study had to be an RCT conducted on human participants that investigated the effect of at least one injection treatment on the management of patellar tendinopathy. Selected studies were required to report either patient-reported outcomes or biological and clinical markers of the tendon healing. The methodological quality of the studies was appraised using the revised Cochrane risk of bias tool for RCTs (RoB 2.0). Nine RCTs on seven types of injections were included in this review, with an overall positive outcome. Pain intensity was measured in all the studies. The VISA P score was the most used outcome measure ( = 8). A wide variety of interventions were compared with injection therapy, including eccentric training, extracorporeal shockwave, and arthroscopy. It can be concluded that the injection treatments can produce promising results in the management of patellar tendinopathy. However, because of the limited number of studies and the disparities in the study populations and protocols, it is not possible to make a firm conclusion on the efficacy of these injection methods, and these results should be inferred with care.

摘要

注射治疗是髌腱病保守治疗中应用最广泛的方法之一。本系统评价的目的是综合随机对照试验的数据,以评估各种注射疗法治疗髌腱病的有效性。我们在科学网、Scopus、PubMed和SPORTDiscus数据库中进行了电子检索。要纳入本系统评价,研究必须是针对人类参与者进行的随机对照试验,且研究至少一种注射治疗对髌腱病治疗的效果。入选的研究需报告患者报告的结局或肌腱愈合的生物学和临床指标。使用修订后的Cochrane随机对照试验偏倚风险工具(RoB 2.0)对研究的方法学质量进行评估。本评价纳入了9项关于7种注射疗法的随机对照试验,总体结果为阳性。所有研究均测量了疼痛强度。VISA P评分是最常用的结局指标(n = 8)。多种干预措施与注射疗法进行了比较,包括离心训练、体外冲击波和关节镜检查。可以得出结论,注射治疗在髌腱病的治疗中可产生有前景的结果。然而,由于研究数量有限以及研究人群和方案存在差异,无法就这些注射方法的疗效得出确凿结论,对这些结果的推断应谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dcd/8999520/ce5ffeee4741/jcm-11-02006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dcd/8999520/ce5ffeee4741/jcm-11-02006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dcd/8999520/ce5ffeee4741/jcm-11-02006-g001.jpg

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2
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BMJ. 2019 Aug 28;366:l4898. doi: 10.1136/bmj.l4898.
3
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BMC Sports Sci Med Rehabil. 2024 Apr 24;16(1):93. doi: 10.1186/s13102-024-00884-8.
4
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Bioengineering (Basel). 2024 Feb 5;11(2):158. doi: 10.3390/bioengineering11020158.
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