Department of Material Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, 4259 Nagatsuta-Cho Midori-Ku, Yokohama 226-8502, Japan.
Life Science Products Division, NOF Corporation, Yebisu Garden Place Tower, 20-3 Ebisu 4-Chome, Shibuya-Ku, Tokyo 150-6019, Japan.
Molecules. 2022 Mar 25;27(7):2130. doi: 10.3390/molecules27072130.
In this paper, we propose a new spectroscopic method to explore the behavior of molecules near polymeric molecular networks of water-containing soft materials such as hydrogels. We demonstrate the analysis of hydrogen bonding states of water in the vicinity of hydrogels (soft contact lenses). In this method, we apply force to hydrated contact lenses to deform them and to modulate the ratio between the signals from bulk and vicinal regions. We then collect spectra at different forces. Finally, we extracted the spectra of the vicinal region using the multivariate curve resolution-alternating least square (MCR-ALS) method. We report the hydration states depending on the chemical structures of hydrogels constituting the contact lenses.
本文提出了一种新的光谱方法，用于研究水合软材料（如水凝胶）中高分子网络附近分子的行为。我们演示了对水在水凝胶（软性隐形眼镜）附近的氢键状态的分析。在该方法中，我们对水合隐形眼镜施加力以使其变形，并调节来自本体和近邻区域的信号之间的比值。然后，我们在不同的力下收集光谱。最后，我们使用多元曲线分辨-交替最小二乘法（MCR-ALS）方法提取近邻区域的光谱。我们根据构成隐形眼镜的水凝胶的化学结构报告了水合状态。
