Monti P, Simoni R, Caramazza R, Bertoluzza A
Centro di Studio sulla Spettroscopia Raman, Dipartimento di Biochimica G. Moruzzi, Università di Bologna, Italy.
Biospectroscopy. 1998;4(6):413-9. doi: 10.1002/(SICI)1520-6343(1998)4:6%3C413::AID-BSPY6%3E3.0.CO;2-G.
Disposable soft contact lenses based on HEMA-MAA hydrogels are examined using Raman and ATR/FTIR vibrational spectroscopies and thermal analysis. The main factors dealing with physical, chemical, and biological biocompatibility are evaluated in relation to those of long-wear soft contact lenses with the aim of individuating the most biocompatible lens. The Raman spectra of HEMA-MAA lenses show that some biocompatibility factors are affected by environmental conditions and, in particular, by changes in pH and ionic strength values.
