• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

疫苗研发中的新科学机遇与旧有障碍

New scientific opportunities and old obstacles in vaccine development.

作者信息

Warren K S

出版信息

Proc Natl Acad Sci U S A. 1986 Dec;83(24):9275-7. doi: 10.1073/pnas.83.24.9275.

DOI:10.1073/pnas.83.24.9275
PMID:3540933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC387120/
Abstract

The present status of and priorities for vaccine development are described, and the historical conditions under which vaccines have been developed are contrasted with newer technologies for such development. Current programs, the opportunities they present, and the obstacles to their implementation are summarized.

摘要

描述了疫苗研发的现状和优先事项,并将疫苗研发的历史条件与此类研发的新技术进行了对比。总结了当前的项目、它们带来的机遇以及实施过程中遇到的障碍。

相似文献

1
New scientific opportunities and old obstacles in vaccine development.疫苗研发中的新科学机遇与旧有障碍
Proc Natl Acad Sci U S A. 1986 Dec;83(24):9275-7. doi: 10.1073/pnas.83.24.9275.
2
Six decades of vaccine development--a personal history.六十年疫苗研发历程——个人经历
Nat Med. 1998 May;4(5 Suppl):507-14. doi: 10.1038/nm0598supp-507.
3
Vaccine Innovations - Past and Future.疫苗创新——过去与未来
N Engl J Med. 2021 Feb 4;384(5):393-396. doi: 10.1056/NEJMp2029466. Epub 2021 Jan 30.
4
Vaccine innovation: lessons from World War II.疫苗创新:二战的经验教训。
J Public Health Policy. 2006;27(1):38-57; discussion 58-60. doi: 10.1057/palgrave.jphp.3200064.
5
A century of innovation in vaccines.
Vaccine. 1999 Oct 29;17 Suppl 3:S7-S10. doi: 10.1016/s0264-410x(99)00287-x.
6
Early Poultry Vaccine Company Development: the Era of Entrepreneurs.早期家禽疫苗公司的发展:企业家时代。
Avian Dis. 2019 Mar 1;63(1):1-8. doi: 10.1637/11922-070918-Hist.1.
7
Vaccines as tools for advancing more than public health: perspectives of a former director of the National Vaccine Program office.
Clin Infect Dis. 2001 Jan 15;32(2):283-8. doi: 10.1086/318461.
8
The winning shot. New vaccine technologies to offer pinpoint attacks on a variety of potentially deadly diseases.制胜一击。新型疫苗技术可精准对抗多种潜在致命疾病。
Mod Healthc. 2005 Nov 14;35(46):52-4.
9
Vaccine preventable diseases: current perspectives in historical context, Part II.疫苗可预防疾病:历史背景下的当前观点,第二部分
Dis Mon. 2007 Oct;53(10):467-528. doi: 10.1016/j.disamonth.2007.09.009.
10
Immunization. Past successes, future challenges.
Infect Dis Clin North Am. 1995 Jun;9(2):325-33.

引用本文的文献

1
Protective Effect of Vaccine Promoted Neutralizing Antibodies against the Intracellular Pathogen .疫苗诱导的中和抗体对细胞内病原体的保护作用
Front Immunol. 2017 Dec 11;8:1652. doi: 10.3389/fimmu.2017.01652. eCollection 2017.
2
Current approaches to vaccine preparation.疫苗制备的当前方法。
Can Vet J. 1990 Mar;31(3):181-9.
3
Fostering partnerships for vaccine development: a delicate fabric.促进疫苗研发的伙伴关系:一张精致的网络。
Bull N Y Acad Med. 1996 Summer;73(1):113-23.
4
Immune responses to wild and vaccine rubella viruses after rubella vaccination.风疹疫苗接种后对野生型和风疹疫苗病毒的免疫反应。
Arch Virol. 1989;106(1-2):63-72. doi: 10.1007/BF01311038.

本文引用的文献

1
USDA biotechnology review criticized and defended.
Science. 1986 Apr 18;232(4748):316. doi: 10.1126/science.11643917.
2
Biotech firm gets another black eye over experiment.生物技术公司因实验再遭负面评价。
Science. 1986 Mar 14;231(4743):1242. doi: 10.1126/science.11643907.
3
Local opposition halts biotechnology test.
Science. 1986 Feb 14;231(4739):667-8. doi: 10.1126/science.11643906.
4
EPA approves field test of altered microbes.美国环境保护局批准对经过改造的微生物进行实地测试。
Science. 1985 Nov 29;230(4729):1015-6. doi: 10.1126/science.11643839.
5
New technology of medicine.
Nature. 1986;321(6073):807. doi: 10.1038/321807a0.
6
NIH plans probe on test of altered virus.
Science. 1986 May 16;232(4752):821-2. doi: 10.1126/science.232.4752.821-a.
7
USDA suspends license for engineered vaccine.
Science. 1986 Apr 25;232(4749):446. doi: 10.1126/science.3457469.
8
Immunization--an adult thing to do.
J Infect Dis. 1985 Jul;152(1):1-3. doi: 10.1093/infdis/152.1.1.