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两种出汗条件下汗液中 Ni、Pb、Cu、As 和 Hg 的排泄。

Excretion of Ni, Pb, Cu, As, and Hg in Sweat under Two Sweating Conditions.

机构信息

Department of Safety, Health and Environmental Engineering, Ming Chi University of Technology, New Taipei 24301, Taiwan.

Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Chiayi 61363, Taiwan.

出版信息

Int J Environ Res Public Health. 2022 Apr 4;19(7):4323. doi: 10.3390/ijerph19074323.

DOI:10.3390/ijerph19074323
PMID:35410004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8998800/
Abstract

Physiologists have long regarded sweating as an effective and safe means of detoxification, and heavy metals are excreted through sweat to reduce the levels of such metals in the body. However, the body can sweat through many means. To elucidate the difference in the excretion of heavy metals among sweating methods, 12 healthy young university students were recruited as participants (6 men and 6 women). Sweat samples were collected from the participants while they were either running on a treadmill or sitting in a sauna cabinet. After they experienced continuous sweating for 20 min, a minimum of 7 mL of sweat was collected from each participant, and the concentrations of nickel (Ni), lead (Pb), copper (Cu), arsenic (As), and mercury (Hg) were analyzed. The results demonstrated that the sweating method affected the excretion of heavy metals in sweat, with the concentrations of Ni, Pb, Cu, and As being significantly higher during dynamic exercise than during sitting in the sauna (all p < 0.05). However, the concentrations of Hg were unaffected by the sweating method. This study suggests that the removal of heavy metals from the body through dynamic exercise may be more effective than removal through static exposure to a hot environment.

摘要

生理学家长期以来一直将出汗视为一种有效且安全的解毒方法,重金属通过汗液排出,以降低体内重金属的含量。但是,人体可以通过多种方式出汗。为了阐明出汗方式对重金属排泄的差异,招募了 12 名健康的年轻大学生作为参与者(6 名男性和 6 名女性)。在参与者在跑步机上跑步或坐在桑拿房时,收集他们的汗液样本。在连续出汗 20 分钟后,从每位参与者身上收集至少 7 毫升的汗液,并分析镍(Ni)、铅(Pb)、铜(Cu)、砷(As)和汞(Hg)的浓度。结果表明,出汗方式影响汗液中重金属的排泄,与坐在桑拿房中相比,动态运动时 Ni、Pb、Cu 和 As 的浓度明显更高(均 p < 0.05)。然而,Hg 的浓度不受出汗方式的影响。本研究表明,通过动态运动从体内去除重金属可能比通过静态暴露于热环境更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9e/8998800/edfd82a7a816/ijerph-19-04323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9e/8998800/7d1a7b466fa0/ijerph-19-04323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9e/8998800/edfd82a7a816/ijerph-19-04323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9e/8998800/7d1a7b466fa0/ijerph-19-04323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9e/8998800/edfd82a7a816/ijerph-19-04323-g002.jpg

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Int J Environ Res Public Health. 2020 May 12;17(10):3377. doi: 10.3390/ijerph17103377.
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Effect of change in ambient temperature on core temperature of female subjects during the daytime and its sex differences.环境温度变化对女性日间核心体温的影响及其性别差异。
Int J Biometeorol. 2019 Aug;63(8):1069-1076. doi: 10.1007/s00484-019-01721-1. Epub 2019 Apr 24.
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Working Up a Good Sweat - The Challenges of Standardising Sweat Collection for Metabolomics Analysis.
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BMC Public Health. 2025 Jun 2;25(1):2049. doi: 10.1186/s12889-025-23333-8.
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The Effect of Physical Activity on Combined Cadmium, Lead, and Mercury Exposure.体育活动对镉、铅和汞联合暴露的影响。
Med Sci (Basel). 2024 Dec 11;12(4):71. doi: 10.3390/medsci12040071.
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Epidermal Wearable Biosensors for Monitoring Biomarkers of Chronic Disease in Sweat.用于监测汗液中慢性疾病生物标志物的表皮可穿戴生物传感器。
Biosensors (Basel). 2023 Feb 23;13(3):313. doi: 10.3390/bios13030313.
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Clin Biochem Rev. 2017 Feb;38(1):13-34.
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A cross sectional study of the relationship between the exposure of pregnant women to military attacks in 2014 in Gaza and the load of heavy metal contaminants in the hair of mothers and newborns.一项关于2014年加沙地带孕妇遭受军事袭击与母亲及新生儿头发中重金属污染物含量之间关系的横断面研究。
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Sweating Rate and Sweat Sodium Concentration in Athletes: A Review of Methodology and Intra/Interindividual Variability.运动员的出汗率和汗钠浓度:方法学和个体内/个体间变异性综述。
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