Department of Chemistry, Jadavpur University, Kolkata 700032, India.
Org Biomol Chem. 2022 May 4;20(17):3491-3494. doi: 10.1039/d2ob00315e.
Styrenes have been functionalized to produce styrenyl dithiocarbamates by a one-pot two-step procedure without using any metal catalysts. Styrene was transformed into a bromo-derivative, which undergoes a domino nucleophilic substitution followed by elimination in the presence of a dithiocarbamate anion and triethylamine to produce -styrenyl dithiocarbamates exclusively. The reaction shows a wide substrate scope and good yields of products.
苯乙烯通过一锅两步法进行功能化，得到苯乙烯基二硫代氨基甲酸盐，无需使用任何金属催化剂。苯乙烯被转化为溴代衍生物，在二硫代氨基甲酸盐阴离子和三乙胺的存在下，通过多米诺亲核取代和消除反应，生成 - 苯乙烯基二硫代氨基甲酸盐。该反应具有广泛的底物范围和良好的产物收率。
