Cancer Discov. 2022 Jun 2;12(6):1402. doi: 10.1158/2159-8290.CD-NB2022-0030.
Preliminary data from a phase I trial of MEDI5752, a bispecific antibody targeting both PD-1 and CTLA4, indicate the drug is well tolerated and active, with durable responses seen across diverse tumor types.
一项针对 MEDI5752(一种同时针对 PD-1 和 CTLA4 的双特异性抗体)的 I 期临床试验的初步数据表明,该药物具有良好的耐受性和活性,在多种肿瘤类型中均观察到持久的反应。