Alzoabi Nasser, Alqahtani Jamal, Algamdi Bader, Almutairi Mohammed, Alratroot Jumana, Alkhaldi Saud, Alqahtani Shatha, Alakloby Omar
Department of Dermatology, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.
Medical Intern College of Medicine, King Faisal University, Alhasa, Saudi Arabia.
Med Arch. 2022 Feb;76(1):72-74. doi: 10.5455/medarh.2022.76.72-74.
Erythema nodosum (EN) is a common form of panniculitis that could be triggered by numerous conditions including infectious and non-infectious conditions. So far, few cases of EN caused by COVID-19 vaccine had been reported.
We report a case of atypical presentation of EN mimicking cellulitis in a patient who received the first dose of the Pfizer-BioNTech COVID-19 vaccine. A 38-year-old healthy woman who developed painful swelling on the left leg one week after receiving the first dose of Pfizer-BioNTech COVID-19 vaccine. Skin biopsy was revealed septal panniculitis. Due to the temporal association and the absence of other identifiable causes, Pfizer-BioNTech COVID-19 vaccine-related EN would be the most likely explanation.
COVID-19 vaccines could be associated with rare side effects that should be reported for a better understanding of related outcomes of COVID-19 vaccination. This case was reported to keep in mind that EN can have atypical presentation as a rare side effect of COVID-19 vaccines.
结节性红斑（EN）是脂膜炎的一种常见形式，可由多种情况引发，包括感染性和非感染性情况。到目前为止，由新冠疫苗引起的EN病例报告较少。
我们报告一例在接种第一剂辉瑞-BioNTech新冠疫苗后出现类似蜂窝织炎的非典型结节性红斑表现的病例。一名38岁健康女性在接种第一剂辉瑞-BioNTech新冠疫苗一周后左腿出现疼痛性肿胀。皮肤活检显示为间隔性脂膜炎。由于时间关联以及缺乏其他可识别的病因，辉瑞-BioNTech新冠疫苗相关的结节性红斑是最可能的解释。
新冠疫苗可能与罕见的副作用有关，应予以报告以更好地了解新冠疫苗接种的相关结果。报告此病例是为了提醒注意结节性红斑可能作为新冠疫苗罕见副作用而有非典型表现。
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