Chen Yuxin, Yao Xuefeng, Wang Xiaolu, Zhang Xuefeng, Zhou Huacong, He Runxia, Liu Quansheng
Inner Mongolia Key Laboratory of High-Value Functional Utilization of Low Rank Carbon Resources, College of Chemical Engineering, Inner Mongolia University of Technology Hohhot 010051 Inner Mongolia China
Chifeng Pharmaceutical Co. Ltd Chifeng 240000 Inner Mongolia China.
RSC Adv. 2021 Apr 13;11(23):13970-13979. doi: 10.1039/d1ra01738a.
The oxytetracycline fermentation broth residue (OFR) is an abundant solid waste in the fermentation industry, which is hazardous but tricky to treat. The resource utilization of the waste OFR is still challenging. In this study, a novel route of using OFR was proposed that OFR was used as the organic ligands to construct a new hafnium based catalyst (Hf-OFR) for Meerwein-Ponndorf-Verley (MPV) reactions of biomass-derived platforms. The acidic groups in OFR were used to coordinate with Hf, and the carbon skeleton structures in OFR were used to form the spatial network structures of the Hf-OFR catalyst. The results showed that the synthesized Hf-OFR catalyst could catalyze the MPV reduction of various carbonyl compounds under relatively mild reaction conditions, with high conversions and yields. Besides, the Hf-OFR catalyst could be recycled at least 5 times with excellent stability in activity and structures. The prepared Hf-OFR catalyst possesses the advantages of high efficiency, a simple preparation process, and low cost in ligands. The proposed strategy of constructing catalysts using OFR may provide new routes for both valuable utilization of the OFR solid waste in the fermentation industry and the construction of efficient catalysts for biomass conversion.
土霉素发酵液残渣（OFR）是发酵工业中一种大量产生的固体废物，具有危害性且处理棘手。OFR废物的资源利用仍然具有挑战性。在本研究中，提出了一种利用OFR的新途径，即将OFR用作有机配体，构建一种新型的基于铪的催化剂（Hf-OFR），用于生物质衍生平台的迈尔外因-彭多夫-韦利（MPV）反应。OFR中的酸性基团用于与铪配位，OFR中的碳骨架结构用于形成Hf-OFR催化剂的空间网络结构。结果表明，合成的Hf-OFR催化剂能够在相对温和的反应条件下催化各种羰基化合物的MPV还原反应，具有高转化率和产率。此外，Hf-OFR催化剂可以循环使用至少5次，在活性和结构方面具有优异的稳定性。制备的Hf-OFR催化剂具有高效、制备过程简单、配体成本低等优点。所提出的利用OFR构建催化剂的策略可能为发酵工业中OFR固体废物的高值化利用以及生物质转化高效催化剂的构建提供新途径。
