Hiwasa T, Yokoyama S, Ha J M, Noguchi S, Sakiyama S
FEBS Lett. 1987 Jan 19;211(1):23-6. doi: 10.1016/0014-5793(87)81266-8.
c-Ha-ras proteins produced by Escherichia coli inhibited the activities of cathepsins B and L which had been partially purified from rat kidney. Furthermore, amino acid sequence homology between c-Ha-ras proteins and thiol proteinase inhibitors has been found.
由大肠杆菌产生的c-Ha-ras蛋白抑制了从大鼠肾脏中部分纯化得到的组织蛋白酶B和L的活性。此外,还发现了c-Ha-ras蛋白与巯基蛋白酶抑制剂之间的氨基酸序列同源性。