Ou Zejin, Gao Yunxia, Jiang Diwei, Cui Jiaxin, Ren Yixian, Tang Shihao, Duan Danping, Yu Danfeng, Wang Zhi
Department of Central Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Key Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Front Oncol. 2022 Mar 29;12:853038. doi: 10.3389/fonc.2022.853038. eCollection 2022.
Secondhand smoke is an important risk factor to breast cancer patients' survival. This article aimed to describe the epidemiological changes of health loss caused by female breast cancer attributable to secondhand smoke from 1990 to 2019.
Data on breast cancer was derived from the Global Burden of Disease study 2019. The epidemiological status and trends were estimated using the number, age-standardized rate (ASR), and estimated annual percentage change (EAPC).
In 2019, secondhand smoke-related breast cancer caused 168.33×10 death, 5242.58×10 years of life lost (YLLs), and 334.03×10 years lived with disability (YLDs) globally. The overall ASR of death and YLLs caused by breast cancer attributable to secondhand smoke presented decreasing trends from 1990 to 2019, with the respective EAPCs of -0.78 and -0.87. Meanwhile, decreasing trends occurred in most geographic regions, particularly that of YLLs in high-income North America (EAPC = -3.35). At the national level, most countries/territories had decreasing trends of death and YLLs, particularly Denmark, in which the respective EAPCs were -4.26 and -4.64. However, the ASR of YLDs showed an increasing trend globally (EAPC = 0.32). Meanwhile, increasing trends were observed in most regions and countries, particularly the Solomon Islands and Lesotho, with the respective EAPCs being 6.18 and 4.33. The changing trends were closely associated with sociodemographic development.
Trends in secondhand smoke-related death and YLLs caused by breast cancer declined from 1990 to 2019. However, secondhand smoke remains a challenge to the patients' longevity and quality of life. The findings informed strategies should be strengthened the control of secondhand smoking.
二手烟是乳腺癌患者生存的一个重要风险因素。本文旨在描述1990年至2019年因二手烟导致的女性乳腺癌所致健康损失的流行病学变化。
乳腺癌数据来源于《2019年全球疾病负担研究》。使用病例数、年龄标准化率（ASR）和估计年百分比变化（EAPC）来估计流行病学状况和趋势。
2019年，全球与二手烟相关的乳腺癌导致168.33×10人死亡、5242.58×10生命年损失（YLLs）和334.03×10伤残调整生命年（YLDs）。1990年至2019年，二手烟所致乳腺癌的总体死亡ASR和YLLs呈下降趋势，EAPC分别为-0.78和-0.87。同时，大多数地理区域出现下降趋势，尤其是高收入的北美洲的YLLs下降趋势（EAPC = -3.35）。在国家层面，大多数国家/地区的死亡和YLLs呈下降趋势，尤其是丹麦，其EAPC分别为-4.26和-4.64。然而，全球YLDs的ASR呈上升趋势（EAPC = 0.32）。同时，大多数地区和国家出现上升趋势，尤其是所罗门群岛和莱索托，EAPC分别为6.18和4.33。这些变化趋势与社会人口发展密切相关。
1990年至2019年，与二手烟相关的乳腺癌死亡和YLLs趋势下降。然而，二手烟仍然是患者长寿和生活质量的一个挑战。研究结果表明应加强二手烟控制策略。
