Zeng Wei, Jiang Haixiao, He Shiwei, Zhang Yukun, Yu Bo, Wang Hui, Wang Cunzu
Department of Clinical Medicine, School of Medicine, Yangzhou University, Yangzhou, China.
Department of Clinical Medicine, Dalian Medical University, Dalian, China.
Front Surg. 2022 Mar 29;9:823770. doi: 10.3389/fsurg.2022.823770. eCollection 2022.
This study was designed to compare the safety and efficacy of unilateral hemilaminectomy conducted under complete neuroendoscopic visualization (UHNV) relative to unilateral hemilaminectomy under total microscopic visualization (UHMV) for the treatment of patients diagnosed with intraspinal tumors.
In total, 41 patients undergoing intraspinal tumor resection at Northern Jiangsu People's Hospital were included in this study, including 20 and 21 patients in the UHNV and UHMV groups, respectively. Intraoperative parameters including incision length, operative duration, number of vertebral laminae removed and intraoperative blood loss, as well as indicators of curative efficacy such as total tumor resection rates and postoperative symptom improvement rates, and safety indicators including complication rates, recurrence rates, spinal deformity rates, spinal instability incidence, and length of stay (LOS), were compared between the two groups.
In contrast to the UHMV group, patients in the UHNV group had a significantly shorter incision length and decreased intraoperative blood loss ( < 0.05), while the operative duration ( > 0.05) showed no statistical difference. Although the postoperative improvement and total tumor resection rates were enhanced, the difference was not statistically significant ( > 0.05). In comparison, the bedridden time and length of stay (LOS) were significantly shortened ( < 0.05) in the UHNV group. However, there were no significant differences in recurrence, incidence of complications, spinal deformity, and spinal instability ( > 0.05).
Collectively, our findings indicate that UHNV is not inferior to the UHMV approach. Moreover, due to its safe and minimally invasive nature, UHNV represents a promising alternative to UHMV as a treatment for patients with intradural extramedullary tumors.
本研究旨在比较在完全神经内镜可视化下进行的单侧半椎板切除术(UHNV)与在全显微镜可视化下进行的单侧半椎板切除术(UHMV)治疗脊髓内肿瘤患者的安全性和有效性。
本研究共纳入41例在苏北人民医院接受脊髓肿瘤切除术的患者,其中UHNV组和UHMV组分别有20例和21例患者。比较两组患者的术中参数,包括切口长度、手术时间、切除的椎板数量和术中失血量,以及疗效指标,如肿瘤全切除率和术后症状改善率,还有安全指标,包括并发症发生率、复发率、脊柱畸形率、脊柱不稳定发生率和住院时间(LOS)。
与UHMV组相比,UHNV组患者的切口长度明显缩短,术中失血量减少(<0.05),而手术时间(>0.05)无统计学差异。虽然术后改善率和肿瘤全切除率有所提高,但差异无统计学意义(>0.05)。相比之下,UHNV组的卧床时间和住院时间(LOS)明显缩短(<0.05)。然而,在复发、并发症发生率、脊柱畸形和脊柱不稳定方面无显著差异(>0.05)。
总体而言,我们的研究结果表明UHNV并不逊于UHMV方法。此外,由于其安全且微创的特性,UHNV作为一种治疗硬脊膜外髓外肿瘤患者的方法,是UHMV的一种有前景的替代方案。