Department of Internal Medicine and Paediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
Int J Infect Dis. 2022 Jul;120:41-43. doi: 10.1016/j.ijid.2022.04.014. Epub 2022 Apr 13.
A woman presented with cough, fever, and dyspnea during a twin pregnancy following a 13th in vitro fertilization procedure. Ultimately, she was diagnosed with miliary tuberculosis and tuberculostatic treatment was initiated, complicated by drug-induced hepatotoxicity. In retrospect, previous pelvic tuberculosis had likely been overlooked. This case report highlights the need to recognize tuberculosis as a cause of infertility even in low-incidence countries and emphasizes that the peripartum period is a major risk factor for drug-induced liver injury.
一位女性在第 13 次体外受精程序后怀双胞胎时出现咳嗽、发热和呼吸困难。最终,她被诊断为粟粒性肺结核,并开始进行抗结核治疗,但出现了药物性肝毒性的并发症。回顾既往病史,可能之前就已经存在盆腔结核而被忽视了。本病例报告强调了即使在发病率低的国家,也需要认识到结核病是导致不孕的原因之一,并强调围产期是药物性肝损伤的主要危险因素。