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体外受精后双胎妊娠并发播散性结核 1 例

A case of disseminated tuberculosis during a twin pregnancy following in vitro fertilization.

机构信息

Department of Internal Medicine and Paediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

出版信息

Int J Infect Dis. 2022 Jul;120:41-43. doi: 10.1016/j.ijid.2022.04.014. Epub 2022 Apr 13.

Abstract

A woman presented with cough, fever, and dyspnea during a twin pregnancy following a 13th in vitro fertilization procedure. Ultimately, she was diagnosed with miliary tuberculosis and tuberculostatic treatment was initiated, complicated by drug-induced hepatotoxicity. In retrospect, previous pelvic tuberculosis had likely been overlooked. This case report highlights the need to recognize tuberculosis as a cause of infertility even in low-incidence countries and emphasizes that the peripartum period is a major risk factor for drug-induced liver injury.

摘要

一位女性在第 13 次体外受精程序后怀双胞胎时出现咳嗽、发热和呼吸困难。最终,她被诊断为粟粒性肺结核,并开始进行抗结核治疗,但出现了药物性肝毒性的并发症。回顾既往病史,可能之前就已经存在盆腔结核而被忽视了。本病例报告强调了即使在发病率低的国家,也需要认识到结核病是导致不孕的原因之一,并强调围产期是药物性肝损伤的主要危险因素。

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