锌对糖尿病中分子信号通路的影响。
The impact of zinc on the molecular signaling pathways in the diabetes disease.
作者信息
Asghari Keyvan, Shargh Zahra, Fatehfar Sina, Chodari Leila, Sameei Parsa
机构信息
Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.
Neurophysiology Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran; Department of Physiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
出版信息
J Trace Elem Med Biol. 2022 Jul;72:126985. doi: 10.1016/j.jtemb.2022.126985. Epub 2022 Apr 11.
Since there's been an upsurge in people with diabetes or pre-diabetes conditions, many studies have been conducted to evaluate approaches for reducing the complications of diabetes. One of the most common therapeutic elements suggested for this purpose is zinc (Zn). Zn has long been shown to positively improve complications of both type 1 and type 2 diabetes. This review aims to provide comprehensive information about the influence of Zn on the various signaling pathways in multiple tissues with diabetic conditions, with great attention to the treatment period and effective dose of Zn.
由于糖尿病或糖尿病前期患者人数激增，人们开展了许多研究来评估降低糖尿病并发症的方法。为此建议的最常见治疗元素之一是锌（Zn）。长期以来，锌已被证明能有效改善1型和2型糖尿病的并发症。本综述旨在提供关于锌对糖尿病状态下多种组织中各种信号通路影响的全面信息，特别关注锌的治疗周期和有效剂量。
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