Department of Otolaryngology- Head and Neck Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Drexel University College of Medicine, Philadelphia, PA, USA.
Am J Otolaryngol. 2022 May-Jun;43(3):103467. doi: 10.1016/j.amjoto.2022.103467. Epub 2022 Apr 9.
To evaluate the relationship between intraoperative ischemia time with acute microvascular free tissue transfer (MFTT) complications in head and neck reconstruction.
A systematic review using PRISMA guidelines was performed. Inclusion encompassed all available studies published and indexed using PubMed, Medline, and Embase. Meta-analyses were performed using the Cochrane Review Manager tool. Methodological Index for Non-Randomized Studies (MINORS), the Revised Cochrane risk-of-bias tool for randomized trials, and the NIH Study Quality Assessment Tool for non-randomized prospective studies.
A total of 430 citations were reviewed. 25 were included in our overall qualitative analysis, and 14 for meta-analysis. When comparing ischemia times for flaps with and without complications, no significant difference was observed (p = 0.98). Additionally, in a separate cohort, no significant effect was realized when correlating ischemia time to overall rates and total complications.
Ischemia time was not significantly different between those with and without acute flap complications.
评估术中缺血时间与头颈部重建中急性微小血管游离组织转移 (MFTT) 并发症之间的关系。
使用 PRISMA 指南进行系统评价。纳入范围包括使用 PubMed、Medline 和 Embase 发表和索引的所有可用研究。使用 Cochrane Review Manager 工具进行荟萃分析。非随机研究的方法学指数 (MINORS)、修订后的 Cochrane 随机试验偏倚风险工具以及 NIH 非随机前瞻性研究质量评估工具。
共审查了 430 条引文。25 项被纳入我们的整体定性分析，14 项进行了荟萃分析。当比较有和无并发症的皮瓣缺血时间时，未观察到显著差异 (p = 0.98)。此外，在单独的队列中，当将缺血时间与总体发生率和总并发症相关联时，也没有发现显著影响。
急性皮瓣并发症患者与无并发症患者的缺血时间无显著差异。
