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A new 2'-hydroxyl protecting group for the automated synthesis of oligoribonucleotides.
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Comparison of 55% TFA/CH2Cl2 and 100% TFA for Boc group removal during solid-phase peptide synthesis.
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DPAGT1 Inhibitors of Capuramycin Analogues and Their Antimigratory Activities of Solid Tumors.
J Med Chem. 2020 Oct 8;63(19):10855-10878. doi: 10.1021/acs.jmedchem.0c00545. Epub 2020 Sep 18.
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Uridine natural products: Challenging targets and inspiration for novel small molecule inhibitors.
Bioorg Med Chem. 2020 Sep 15;28(18):115661. doi: 10.1016/j.bmc.2020.115661. Epub 2020 Jul 30.
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Simplified Novel Muraymycin Analogues; using a Serine Template Strategy for Linking Key Pharmacophores.
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A practical synthesis of a novel DPAGT1 inhibitor, aminouridyl phenoxypiperidinbenzyl butanamide (APPB) for in vivo studies.
MethodsX. 2019 Sep 27;6:2305-2321. doi: 10.1016/j.mex.2019.09.031. eCollection 2019.
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Structure-based drug discovery by targeting -glycan biosynthesis, dolichyl-phosphate -acetylglucosaminephosphotransferase.
Future Med Chem. 2019 May;11(9):927-933. doi: 10.4155/fmc-2018-0405. Epub 2019 Mar 25.
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Semisynthesis of an Anticancer DPAGT1 Inhibitor from a Muraymycin Biosynthetic Intermediate.
Org Lett. 2019 Feb 15;21(4):876-879. doi: 10.1021/acs.orglett.8b03716. Epub 2019 Jan 30.
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Aminoribosylated Analogues of Muraymycin Nucleoside Antibiotics.
Molecules. 2018 Nov 26;23(12):3085. doi: 10.3390/molecules23123085.

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