Jahn Beate, Friedrich Sarah, Behnke Joachim, Engel Joachim, Garczarek Ursula, Münnich Ralf, Pauly Markus, Wilhelm Adalbert, Wolkenhauer Olaf, Zwick Markus, Siebert Uwe, Friede Tim
Institute of Public Health, Medical Decision Making and Health Technology Assessment, Department of Public Health, Health Services Research and Health Technology Assessment, UMIT - University for Health Sciences, Medical Informatics and Technology, Hall i.T., Austria.
Department of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.
Adv Stat Anal. 2022;106(3):349-382. doi: 10.1007/s10182-022-00439-7. Epub 2022 Apr 7.
A pandemic poses particular challenges to decision-making because of the need to continuously adapt decisions to rapidly changing evidence and available data. For example, which countermeasures are appropriate at a particular stage of the pandemic? How can the severity of the pandemic be measured? What is the effect of vaccination in the population and which groups should be vaccinated first? The process of decision-making starts with data collection and modeling and continues to the dissemination of results and the subsequent decisions taken. The goal of this paper is to give an overview of this process and to provide recommendations for the different steps from a statistical perspective. In particular, we discuss a range of modeling techniques including mathematical, statistical and decision-analytic models along with their applications in the COVID-19 context. With this overview, we aim to foster the understanding of the goals of these modeling approaches and the specific data requirements that are essential for the interpretation of results and for successful interdisciplinary collaborations. A special focus is on the role played by data in these different models, and we incorporate into the discussion the importance of statistical literacy and of effective dissemination and communication of findings.
大流行给决策带来了特殊挑战,因为需要不断根据迅速变化的证据和现有数据调整决策。例如,在大流行的特定阶段哪些应对措施是合适的?如何衡量大流行的严重程度?疫苗接种在人群中的效果如何,哪些群体应优先接种?决策过程始于数据收集和建模,并持续到结果的传播以及随后做出的决策。本文的目的是概述这一过程,并从统计角度为不同步骤提供建议。特别是,我们讨论了一系列建模技术,包括数学、统计和决策分析模型,以及它们在新冠疫情背景下的应用。通过这一概述,我们旨在促进对这些建模方法目标的理解,以及对解释结果和成功开展跨学科合作至关重要的特定数据要求的理解。特别关注数据在这些不同模型中所起的作用,并且我们在讨论中纳入了统计素养以及有效传播和交流研究结果的重要性。