Jariwala Pankaj, Jadhav Kartik, Khetan Saket
Department of Cardiology, Yashoda Hospitals, Somajiguda, Hyderabad, 500082, Telangana, India.
J Cardiol Cases. 2022 Aug;26(2):139-143. doi: 10.1016/j.jccase.2022.03.019. Epub 2022 Apr 11.
As a primary cause, intracardiac thrombi are seen in a variety of cardiac conditions such as acute anterior myocardial infarctions and dilated cardiomyopathy. However, there are secondary predisposing conditions that increase the risk of clot formation in normally functioning ventricles. Migration or embolization of thrombus produced elsewhere, such as pulmonary thrombo-embolism, may occur at times. However, the current coronavirus disease 2019 (COVID-19) pandemic has resulted in a variety of intracardiac or extracardiac thrombi formations due to systemic inflammation and activation of the clotting system. We present a unique and rare case in association with alcoholic dilated cardiomyopathy and COVID-19, which resulted in the development of multiple biventricular thrombi.
•Significant systolic dysfunction is unusual, especially in people with prolonged alcoholism.•The hypercoagulable condition of coronavirus disease 2019 (COVID-19), combined with myocardial damage secondary to alcohol, can result in extensive intracardiac thrombosis.•Thrombotic manifestations in COVID-19 are associated with a high mortality rate.
作为主要病因,心内血栓可见于多种心脏疾病,如急性前壁心肌梗死和扩张型心肌病。然而,存在一些继发的易患因素会增加正常功能心室形成血栓的风险。有时,血栓会从其他部位迁移或栓塞,如肺血栓栓塞。然而,当前的2019冠状病毒病(COVID - 19)大流行由于全身炎症和凝血系统激活导致了多种心内或心外血栓形成。我们报告一例与酒精性扩张型心肌病和COVID - 19相关的独特罕见病例,该病例导致双心室多发血栓形成。
•严重收缩功能障碍并不常见,尤其是在长期酗酒者中。•2019冠状病毒病(COVID - 19)的高凝状态,加上酒精继发的心肌损伤,可导致广泛的心内血栓形成。•COVID - 19中的血栓表现与高死亡率相关。