Cocchi R
Acta Psychiatr Belg. 1978 Mar-Apr;78(2):407-24.
A detailed presentation of 15 case-histories of subjects of both sexes, drawn from all decennies of life from the first to the eight, suggesting a syndrome originated from a possible GABA deficiency, is carefully made. Such syndrome is believed to be characterized by basic depressive state, loss of the habit of stretching oneself, sleep disorders, mostly with early morning awakening, constipation and nuchal headache. The above symptoms have been associated to a deficiency of GABA after noting the very speed recovery after administration of N-dipropylacetic acid, an inhibitor of GABA transaminase.
精心呈现了15个男女病例史，涵盖从一岁到八岁的各个年龄段，提示可能由GABA缺乏引发一种综合征。该综合征被认为具有以下特征：基本抑郁状态、伸展身体习惯丧失、睡眠障碍（主要是早醒）、便秘和颈部头痛。在注意到给予GABA转氨酶抑制剂N - 二丙基乙酸后症状迅速缓解后，上述症状与GABA缺乏相关联。
